Identity
HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
BHLHC58,MAD,MAD1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4084
MIM: 600021
HGNC: 6761
Ensembl: ENSG00000059728
Variants:
dbSNP: 4084
ClinVar: 4084
TCGA: ENSG00000059728
COSMIC: MXD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000059728 | ENST00000264444 | Q05195 |
| ENSG00000059728 | ENST00000409442 | F8WBI0 |
| ENSG00000059728 | ENST00000435990 | C9JBE8 |
| ENSG00000059728 | ENST00000540449 | Q05195 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33537096 | 2021 | Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma. | 7 |
| 34761715 | 2021 | MXD1 is a Potential Prognostic Biomarker and Correlated With Specific Molecular Change and Tumor Microenvironment Feature in Esophageal Squamous Cell Carcinoma. | 2 |
| 33537096 | 2021 | Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma. | 7 |
| 34761715 | 2021 | MXD1 is a Potential Prognostic Biomarker and Correlated With Specific Molecular Change and Tumor Microenvironment Feature in Esophageal Squamous Cell Carcinoma. | 2 |
| 31635836 | 2020 | The MicroRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes. | 6 |
| 32794336 | 2020 | MXD1 regulates the H9N2 and H1N1 influenza A virus-induced chemokine expression and their replications in human macrophage. | 3 |
| 31635836 | 2020 | The MicroRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes. | 6 |
| 32794336 | 2020 | MXD1 regulates the H9N2 and H1N1 influenza A virus-induced chemokine expression and their replications in human macrophage. | 3 |
| 30419548 | 2018 | MXD1 regulates the imatinib resistance of chronic myeloid leukemia cells by repressing BCR-ABL1 expression. | 0 |
| 30419548 | 2018 | MXD1 regulates the imatinib resistance of chronic myeloid leukemia cells by repressing BCR-ABL1 expression. | 0 |
| 28543796 | 2017 | Mxd1 mediates hypoxia-induced cisplatin resistance in osteosarcoma cells by repression of the PTEN tumor suppressor gene. | 13 |
| 28543796 | 2017 | Mxd1 mediates hypoxia-induced cisplatin resistance in osteosarcoma cells by repression of the PTEN tumor suppressor gene. | 13 |
| 26698869 | 2016 | TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction. | 2 |
| 27520398 | 2016 | miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1. | 13 |
| 27588501 | 2016 | MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis. | 11 |
Citation
Dessen P
MXD1 (MAX dimerization protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/214/mxd1
