Identity
HGNC
LOCATION
9p23
LOCUSID
ALIAS
CTF,HMGIC/NFIB,MACID,NF-I/B,NF1-B,NFI-B,NFI-RED,NFIB2,NFIB3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4781
MIM: 600728
HGNC: 7785
Ensembl: ENSG00000147862
Variants:
dbSNP: 4781
ClinVar: 4781
TCGA: ENSG00000147862
COSMIC: NFIB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38385986 | 2024 | Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6-catalyzed metabolism of solanidine. | 1 |
| 38385986 | 2024 | Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6-catalyzed metabolism of solanidine. | 1 |
| 36152308 | 2023 | Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits. | 1 |
| 36369883 | 2023 | Transcriptional regulation of NDUFA4L2 by NFIB induces sorafenib resistance by decreasing reactive oxygen species in hepatocellular carcinoma. | 6 |
| 36730637 | 2023 | Knockdown of circ-PIP5K1A overcomes resistance to cisplatin in ovarian cancer by miR-942-5p/NFIB axis. | 5 |
| 36756855 | 2023 | Marked intrafamilial variability of clinical and neuroimaging manifestations in NFIB-related developmental disorder. | 0 |
| 37405427 | 2023 | CircIFFO1 suppresses tumor growth and metastasis of cutaneous squamous cell carcinoma by targeting the miR-424-5p/NFIB axis. | 0 |
| 37604829 | 2023 | NFIB facilitates replication licensing by acting as a genome organizer. | 0 |
| 36152308 | 2023 | Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits. | 1 |
| 36369883 | 2023 | Transcriptional regulation of NDUFA4L2 by NFIB induces sorafenib resistance by decreasing reactive oxygen species in hepatocellular carcinoma. | 6 |
| 36730637 | 2023 | Knockdown of circ-PIP5K1A overcomes resistance to cisplatin in ovarian cancer by miR-942-5p/NFIB axis. | 5 |
| 36756855 | 2023 | Marked intrafamilial variability of clinical and neuroimaging manifestations in NFIB-related developmental disorder. | 0 |
| 37405427 | 2023 | CircIFFO1 suppresses tumor growth and metastasis of cutaneous squamous cell carcinoma by targeting the miR-424-5p/NFIB axis. | 0 |
| 37604829 | 2023 | NFIB facilitates replication licensing by acting as a genome organizer. | 0 |
| 34969759 | 2022 | Nuclear Factor IA Is Down-regulated in Muscle-invasive and High-grade Bladder Cancers. | 3 |
Citation
Dessen P
NFIB (nuclear factor I B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/253/nfib
