ZNF146 (zinc finger protein 146)
2000-10-01 Gérard.Goubin AffiliationLaboratoire dOncogenöse, UMR147 CNRS, Section de recherche, Institut Curie, Paris, France
Proteins
Description
33 kDa; a kruppel zinc finger protein consisting of 10 zinc finger motives, preceeded by 10 amino acids and followed by 2 amino acids
Expression
in most proliferating tissues
Localisation
nucleus
Function
represse gene expression through a consensus motive
Implicated in
Disease
tumors of the exocrine pancreas
Cytogenetics
amplification of the 19q13.1 region in a subset of pancreatic tumors
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 8107129 | 1994 | The OZF gene encodes a protein consisting essentially of zinc finger motifs. | Le Chalony C et al |
Other Information
Locus ID:
NCBI: 7705
MIM: 601505
HGNC: 12931
Ensembl: ENSG00000167635
Variants:
dbSNP: 7705
ClinVar: 7705
TCGA: ENSG00000167635
COSMIC: ZNF146
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167635 | ENST00000443387 | Q15072 |
| ENSG00000167635 | ENST00000456324 | Q15072 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38614125 | 2024 | ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells. | 0 |
| 38614125 | 2024 | ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells. | 0 |
| 37762228 | 2023 | Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis. | 1 |
| 37762228 | 2023 | Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis. | 1 |
| 35100360 | 2022 | ZNF146/OZF and ZNF507 target LINE-1 sequences. | 2 |
| 35100360 | 2022 | ZNF146/OZF and ZNF507 target LINE-1 sequences. | 2 |
| 33394291 | 2021 | LncRNA KCNQ1OT1 acts as miR-216b-5p sponge to promote colorectal cancer progression via up-regulating ZNF146. | 11 |
| 33394291 | 2021 | LncRNA KCNQ1OT1 acts as miR-216b-5p sponge to promote colorectal cancer progression via up-regulating ZNF146. | 11 |
| 32267586 | 2020 | OZF is a Claspin-interacting protein essential to maintain the replication fork progression rate under replication stress. | 3 |
| 32267586 | 2020 | OZF is a Claspin-interacting protein essential to maintain the replication fork progression rate under replication stress. | 3 |
| 15838871 | 2005 | Zinc finger protein overexpressed in colon carcinoma interacts with the telomeric protein hRap1. | 6 |
| 15881673 | 2005 | A Kruppel zinc finger of ZNF 146 interacts with the SUMO-1 conjugating enzyme UBC9 and is sumoylated in vivo. | 3 |
| 15838871 | 2005 | Zinc finger protein overexpressed in colon carcinoma interacts with the telomeric protein hRap1. | 6 |
| 15881673 | 2005 | A Kruppel zinc finger of ZNF 146 interacts with the SUMO-1 conjugating enzyme UBC9 and is sumoylated in vivo. | 3 |
Citation
Gérard.Goubin
ZNF146 (zinc finger protein 146)
Atlas Genet Cytogenet Oncol Haematol. 2000-10-01
Online version: http://atlasgeneticsoncology.org/gene/267/znf146
