TRG (T cell Receptor Gamma)
2000-07-01 Marie-Paule Lefranc AffiliationIMGT, LIGM, IGH, UPR CNRS 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France
Identity
HGNC
LOCATION
7p14
IMAGE
LEGEND
for complete Figure, see: chromosome 7, IMGT (The International ImMunoGeneTics information system ®) © Copyright 1995-2017 IMGT, IMGT is a CNRS trademark
LOCUSID
ALIAS
TCRG,TRG@
FUSION GENES
DNA/RNA
TRG
V-GENE: Green box: Functional; Yellow box: Open reading frame; Red: Pseudogene; Triangle: Not sequenced.
J-GENE: Grey: Functional .
C-GENE: Blue: Functional.
for complete Figure, see: locus TRG, IMGT (The International ImMunoGeneTics information system ®) © Copyright 1995-2017 IMGT, IMGT is a CNRS trademark
V-GENE: Green box: Functional; Yellow box: Open reading frame; Red: Pseudogene; Triangle: Not sequenced.
J-GENE: Grey: Functional .
C-GENE: Blue: Functional.
for complete Figure, see: locus TRG, IMGT (The International ImMunoGeneTics information system ®) © Copyright 1995-2017 IMGT, IMGT is a CNRS trademark
Description
Mutations
Note
Mutations which correspond to allelic polymorphisms of the functional germline TRGV, TRGJ and TRGC genes are described in the IMGT database: (IMGT Repertoire>Alignments of alleles)
Implicated in
Entity name
Inversions which result from errors of the recombinase enzyme complexe (RAG1, RAG2, etc.), responsable of the Immunoglobulin and T cell receptor V-J and V-D-J rearrangements. TRGV or TRGJ recombination signals or isolated heptamer are observed at the breakpoints
Other Information
Locus ID:
Variants:
dbSNP: 6965
ClinVar: 6965
COSMIC: TRG
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34365017 | 2021 | Memory and naïve gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy. | 5 |
| 34365017 | 2021 | Memory and naïve gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy. | 5 |
| 30764544 | 2019 | Early Pregnancy Human Decidua is Enriched with Activated, Fully Differentiated and Pro-Inflammatory Gamma/Delta T Cells with Diverse TCR Repertoires. | 22 |
| 30764544 | 2019 | Early Pregnancy Human Decidua is Enriched with Activated, Fully Differentiated and Pro-Inflammatory Gamma/Delta T Cells with Diverse TCR Repertoires. | 22 |
| 28285814 | 2017 | Thymic Determinants of γδ T Cell Differentiation. | 65 |
| 28368347 | 2017 | The Role of Th-17 Cells and γδ T-Cells in Modulating the Systemic Inflammatory Response to Severe Burn Injury. | 16 |
| 28285814 | 2017 | Thymic Determinants of γδ T Cell Differentiation. | 65 |
| 28368347 | 2017 | The Role of Th-17 Cells and γδ T-Cells in Modulating the Systemic Inflammatory Response to Severe Burn Injury. | 16 |
| 27078021 | 2016 | Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study. | 24 |
| 27210746 | 2016 | RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor. | 59 |
| 27373969 | 2016 | Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications. | 15 |
| 27412930 | 2016 | [Homology modeling and eukaryotic expression of a modified αβ TCR harboring the immunoglobulin-like domain of γδ TCR]. | 0 |
| 27078021 | 2016 | Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study. | 24 |
| 27210746 | 2016 | RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor. | 59 |
| 27373969 | 2016 | Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications. | 15 |
Citation
Marie-Paule Lefranc
TRG (T cell Receptor Gamma)
Atlas Genet Cytogenet Oncol Haematol. 2000-07-01
Online version: http://atlasgeneticsoncology.org/gene/268/trg-(t-cell-receptor-gamma)
