Identity
HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
MGC:45012,RNF117,TRAP,TRAP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7186
MIM: 601895
HGNC: 12032
Ensembl: ENSG00000127191
Variants:
dbSNP: 7186
ClinVar: 7186
TCGA: ENSG00000127191
COSMIC: TRAF2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38411080 | 2024 | CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. | 0 |
| 38419066 | 2024 | Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway. | 0 |
| 38411080 | 2024 | CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. | 0 |
| 38419066 | 2024 | Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway. | 0 |
| 37081115 | 2023 | The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway. | 5 |
| 37415241 | 2023 | TRAF2 promotes M2-polarized tumor-associated macrophage infiltration, angiogenesis and cancer progression by inhibiting autophagy in clear cell renal cell carcinoma. | 7 |
| 37516734 | 2023 | The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2. | 0 |
| 38062811 | 2023 | Silencing of CPNE1-TRAF2 Axis Restrains the Development of Pancreatic Cancer. | 2 |
| 37081115 | 2023 | The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway. | 5 |
| 37415241 | 2023 | TRAF2 promotes M2-polarized tumor-associated macrophage infiltration, angiogenesis and cancer progression by inhibiting autophagy in clear cell renal cell carcinoma. | 7 |
| 37516734 | 2023 | The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2. | 0 |
| 38062811 | 2023 | Silencing of CPNE1-TRAF2 Axis Restrains the Development of Pancreatic Cancer. | 2 |
| 35257890 | 2022 | Revisited role of TRAF2 and TRAF2 C-terminal domain in endoplasmic reticulum stress-induced autophagy in HAP1 leukemia cells. | 1 |
| 35257890 | 2022 | Revisited role of TRAF2 and TRAF2 C-terminal domain in endoplasmic reticulum stress-induced autophagy in HAP1 leukemia cells. | 1 |
| 33229071 | 2021 | HtrA2 is required for inflammatory responses in BMDMs via controlling TRAF2 stability in collagen-induced arthritis. | 6 |
Citation
Dessen P
TRAF2 (TNF receptor associated factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/270/traf2
