GDF3 (growth differentiation factor 3)

2003-05-01  

Identity

HGNC
GDF3
LOCATION
12p13.31
LOCUSID
9573
ALIAS
KFS3,MCOP7,MCOPCB6

Other Information

Locus ID:

NCBI: 9573
MIM: 606522
HGNC: 4218
Ensembl: ENSG00000184344

Variants:

dbSNP: 9573
ClinVar: 9573
TCGA: ENSG00000184344
COSMIC: GDF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184344ENST00000329913Q9NR23

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
364842602023Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction.3
386399492023[Expression and significance analysis of GDF3 in testicular cancer based on TCGA and GTEx databases].0
364842602023Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction.3
386399492023[Expression and significance analysis of GDF3 in testicular cancer based on TCGA and GTEx databases].0
356327462022Increased Serum Levels of Growth-Differentiation Factor 3 (GDF3) and Inflammasome-Related Markers in Pregnant Women during Acute Zika Virus Infection.1
356327462022Increased Serum Levels of Growth-Differentiation Factor 3 (GDF3) and Inflammasome-Related Markers in Pregnant Women during Acute Zika Virus Infection.1
297359712018Functional and In Silico Assessment of GDF3 Gene Variants in a Chinese Congenital Scoliosis Population.0
297359712018Functional and In Silico Assessment of GDF3 Gene Variants in a Chinese Congenital Scoliosis Population.0
278034512016Growth and Differentiation Factor 3 Is Transcriptionally Regulated by OCT4 in Human Embryonic Carcinoma Cells.1
278034512016Growth and Differentiation Factor 3 Is Transcriptionally Regulated by OCT4 in Human Embryonic Carcinoma Cells.1
253720142015A novel variation of GDF3 in Chinese Han children with a broad phenotypic spectrum of non-syndromic CHDs.1
253720142015A novel variation of GDF3 in Chinese Han children with a broad phenotypic spectrum of non-syndromic CHDs.1
218050892012The conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cells.6
223051022012Growth differentiation factor 3 is induced by bone morphogenetic protein 6 (BMP-6) and BMP-7 and increases luteinizing hormone receptor messenger RNA expression in human granulosa cells.7
224881702012GDF3 inhibits the growth of breast cancer cells and promotes the apoptosis induced by Taxol.9

Citation

Dessen P

GDF3 (growth differentiation factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/332