Identity
HGNC
LOCATION
17q22
LOCUSID
ALIAS
BROVCA3,FANCO,R51H3,RAD51L2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5889
MIM: 602774
HGNC: 9820
Ensembl: ENSG00000108384
Variants:
dbSNP: 5889
ClinVar: 5889
TCGA: ENSG00000108384
COSMIC: RAD51C
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38330859 | 2024 | Variants in the first methionine of RAD51C are homologous recombination proficient due to an alternative start site. | 0 |
| 38330859 | 2024 | Variants in the first methionine of RAD51C are homologous recombination proficient due to an alternative start site. | 0 |
| 36411032 | 2023 | UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2. | 7 |
| 36562461 | 2023 | Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection. | 2 |
| 37031326 | 2023 | SNV/indel hypermutator phenotype in biallelic RAD51C variant: Fanconi anemia. | 0 |
| 37253112 | 2023 | Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C. | 1 |
| 37344587 | 2023 | Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. | 10 |
| 37344589 | 2023 | Structural insights into BCDX2 complex function in homologous recombination. | 7 |
| 37488098 | 2023 | RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. | 6 |
| 36411032 | 2023 | UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2. | 7 |
| 36562461 | 2023 | Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection. | 2 |
| 37031326 | 2023 | SNV/indel hypermutator phenotype in biallelic RAD51C variant: Fanconi anemia. | 0 |
| 37253112 | 2023 | Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C. | 1 |
| 37344587 | 2023 | Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. | 10 |
| 37344589 | 2023 | Structural insights into BCDX2 complex function in homologous recombination. | 7 |
Citation
Dessen P
RAD51C (RAD51 paralog C)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/346/rad51c
