Identity
HGNC
LOCATION
1p34.1
LOCUSID
ALIAS
HR54,RAD54A,hHR54,hRAD54
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8438
MIM: 603615
HGNC: 9826
Ensembl: ENSG00000085999
Variants:
dbSNP: 8438
ClinVar: 8438
TCGA: ENSG00000085999
COSMIC: RAD54L
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Homologous recombination | KEGG | ko03440 |
| Homologous recombination | KEGG | hsa03440 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38593124 | 2024 | Overexpression of RAD54L attenuates osteoarthritis by suppressing the HIF-1α/VEGF signaling pathway: Bioinformatics analysis and experimental validation. | 0 |
| 38593124 | 2024 | Overexpression of RAD54L attenuates osteoarthritis by suppressing the HIF-1α/VEGF signaling pathway: Bioinformatics analysis and experimental validation. | 0 |
| 36454390 | 2023 | DNA repair/recombination protein 54L promotes the progression of lung adenocarcinoma by activating mTORC1 pathway. | 2 |
| 36454390 | 2023 | DNA repair/recombination protein 54L promotes the progression of lung adenocarcinoma by activating mTORC1 pathway. | 2 |
| 36071250 | 2022 | Rad54L promotes bladder cancer progression by regulating cell cycle and cell senescence. | 4 |
| 36071250 | 2022 | Rad54L promotes bladder cancer progression by regulating cell cycle and cell senescence. | 4 |
| 34079088 | 2021 | Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L. | 18 |
| 34169999 | 2021 | Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort. | 1 |
| 34079088 | 2021 | Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L. | 18 |
| 34169999 | 2021 | Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort. | 1 |
| 32333827 | 2020 | Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. | 6 |
| 33261027 | 2020 | E2F1 Promotes Progression of Bladder Cancer by Modulating RAD54L Involved in Homologous Recombination Repair. | 20 |
| 32333827 | 2020 | Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. | 6 |
| 33261027 | 2020 | E2F1 Promotes Progression of Bladder Cancer by Modulating RAD54L Involved in Homologous Recombination Repair. | 20 |
| 29295984 | 2018 | RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions. | 13 |
Citation
Dessen P
RAD54L (RAD54 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/348/rad54l
