Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5897
MIM: 179616
HGNC: 9832
Ensembl: ENSG00000175097
Variants:
dbSNP: 5897
ClinVar: 5897
TCGA: ENSG00000175097
COSMIC: RAG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000175097 | ENST00000311485 | P55895 |
| ENSG00000175097 | ENST00000527033 | E9PQB9 |
| ENSG00000175097 | ENST00000529083 | E9PPU5 |
| ENSG00000175097 | ENST00000618712 | P55895 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37724703 | 2024 | Heterogeneity in RAG1 and RAG2 deficiency: 35 cases from a single-centre. | 1 |
| 38350907 | 2024 | From variant of uncertain significance to likely pathogenic in two siblings with atypical RAG2 Deficiency: a case report and review of the literature. | 0 |
| 37724703 | 2024 | Heterogeneity in RAG1 and RAG2 deficiency: 35 cases from a single-centre. | 1 |
| 38350907 | 2024 | From variant of uncertain significance to likely pathogenic in two siblings with atypical RAG2 Deficiency: a case report and review of the literature. | 0 |
| 36279417 | 2023 | Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT. | 11 |
| 37573280 | 2023 | A novel loss of function mutation in the PHD domain of the RAG2 gene, affecting zinc-binding affinity. | 0 |
| 36279417 | 2023 | Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT. | 11 |
| 37573280 | 2023 | A novel loss of function mutation in the PHD domain of the RAG2 gene, affecting zinc-binding affinity. | 0 |
| 35902638 | 2022 | Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet(+) B cells. | 14 |
| 36270284 | 2022 | Rag2(-/-) accelerates lipofuscin accumulation in the brain: Implications for human stem cell brain transplantation studies. | 3 |
| 35902638 | 2022 | Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet(+) B cells. | 14 |
| 36270284 | 2022 | Rag2(-/-) accelerates lipofuscin accumulation in the brain: Implications for human stem cell brain transplantation studies. | 3 |
| 33796120 | 2021 | The Interplay Between Chromatin Architecture and Lineage-Specific Transcription Factors and the Regulation of Rag Gene Expression. | 14 |
| 33954879 | 2021 | Clinical Manifestations, Mutational Analysis, and Immunological Phenotype in Patients with RAG1/2 Mutations: First Cases Series from Mexico and Description of Two Novel Mutations. | 2 |
| 34382351 | 2021 | Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-) Rag2(-/-) IL2rg(-/-) Rats. | 4 |
Citation
Dessen P
RAG2 (recombination activating 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/351/rag2
