CDC14B (cell division cycle 14B)

2003-06-01  

Identity

HGNC
CDC14B
LOCATION
9q22.33
LOCUSID
8555
ALIAS
CDC14B3,Cdc14B1,Cdc14B2,hCDC14B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8555
MIM: 603505
HGNC: 1719
Ensembl: ENSG00000081377

Variants:

dbSNP: 8555
ClinVar: 8555
TCGA: ENSG00000081377
COSMIC: CDC14B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000081377ENST00000375240O60729
ENSG00000081377ENST00000375241O60729
ENSG00000081377ENST00000375242O60729
ENSG00000081377ENST00000412285H7C3U8
ENSG00000081377ENST00000415608Q5JU07
ENSG00000081377ENST00000452280H0Y577
ENSG00000081377ENST00000463569O60729
ENSG00000081377ENST00000474602O60729

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell cycleKEGGko04110
Cell cycleKEGGhsa04110
Signal TransductionREACTOMER-HSA-162582
MAPK family signaling cascadesREACTOMER-HSA-5683057
MAPK6/MAPK4 signalingREACTOMER-HSA-5687128

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368982992023CDC14B is a favorable biomarker for recurrence and prognosis of GBM.1
374931852023The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans.3
368982992023CDC14B is a favorable biomarker for recurrence and prognosis of GBM.1
374931852023The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans.3
333283272021Human cells lacking CDC14A and CDC14B show differences in ciliogenesis but not in mitotic progression.6
333283272021Human cells lacking CDC14A and CDC14B show differences in ciliogenesis but not in mitotic progression.6
323665552020MiR-1247-5p Functions as a Tumor Suppressor in Human Astroglioma Cells by Targeting CDC14B.6
333789382020Downregulation of CDC14B in 5218 breast cancer patients: A novel prognosticator for triple-negative breast cancer.3
323665552020MiR-1247-5p Functions as a Tumor Suppressor in Human Astroglioma Cells by Targeting CDC14B.6
333789382020Downregulation of CDC14B in 5218 breast cancer patients: A novel prognosticator for triple-negative breast cancer.3
301381062019MicroRNA-1225-5p acts as a tumor-suppressor in laryngeal cancer via targeting CDC14B.12
301381062019MicroRNA-1225-5p acts as a tumor-suppressor in laryngeal cancer via targeting CDC14B.12
281815472017Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations.9
281815472017Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations.9
260237732015Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis.14

Citation

Dessen P

CDC14B (cell division cycle 14B)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40001