CDH12 (cadherin 12)

2003-11-01  

Identity

HGNC
CDH12
LOCATION
5p14.3
LOCUSID
1010
ALIAS
CDHB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1010
MIM: 600562
HGNC: 1751
Ensembl: ENSG00000154162

Variants:

dbSNP: 1010
ClinVar: 1010
TCGA: ENSG00000154162
COSMIC: CDH12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154162ENST00000382254P55289
ENSG00000154162ENST00000504376P55289
ENSG00000154162ENST00000522262P55289

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Adherens junctions interactionsREACTOMER-HSA-418990

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
361418532022The Role of Cadherin 12 (CDH12) in the Peritoneal Fluid among Patients with Endometriosis and Endometriosis-Related Infertility.8
361418532022The Role of Cadherin 12 (CDH12) in the Peritoneal Fluid among Patients with Endometriosis and Endometriosis-Related Infertility.8
343854562021An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer.58
343854562021An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer.58
319116112020Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family.3
319116112020Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family.3
267624122016Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT.23
267624122016Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT.23
215734962011CDH12 promotes the invasion of salivary adenoid cystic carcinoma.11
215734962011CDH12 promotes the invasion of salivary adenoid cystic carcinoma.11
194737192010Identification of genes associated with non-small-cell lung cancer promotion and progression.57
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.26
194737192010Identification of genes associated with non-small-cell lung cancer promotion and progression.57
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

CDH12 (cadherin 12)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40017/css/gene-fusions/css/template-nav.css