CDH4 (cadherin 4)

2003-11-01  

Identity

HGNC
CDH4
LOCATION
20q13.33
LOCUSID
1002
ALIAS
CAD4,R-CAD,RCAD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1002
MIM: 603006
HGNC: 1763
Ensembl: ENSG00000179242

Variants:

dbSNP: 1002
ClinVar: 1002
TCGA: ENSG00000179242
COSMIC: CDH4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179242ENST00000543233P55283
ENSG00000179242ENST00000611855A0A087WX99
ENSG00000179242ENST00000614565P55283

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Adherens junctions interactionsREACTOMER-HSA-418990
Developmental BiologyREACTOMER-HSA-1266738
MyogenesisREACTOMER-HSA-525793
CDO in myogenesisREACTOMER-HSA-375170

References

Pubmed IDYearTitleCitations
384021592024Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin.1
384021592024Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin.1
372372992023CDH4 inhibits ferroptosis in oral squamous cell carcinoma cells.2
381433732023Understanding the Role of CDH4 in Multiple System Atrophy Brain.0
372372992023CDH4 inhibits ferroptosis in oral squamous cell carcinoma cells.2
381433732023Understanding the Role of CDH4 in Multiple System Atrophy Brain.0
350649102022Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression.2
363622802022Alu Deletions in LAMA2 and CDH4 Genes Are Key Components of Polygenic Predictors of Longevity.1
350649102022Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression.2
363622802022Alu Deletions in LAMA2 and CDH4 Genes Are Key Components of Polygenic Predictors of Longevity.1
327572702021Regulatory CDH4 Genetic Variants Associate With Risk to Develop Capecitabine-Induced Hand-Foot Syndrome.5
327572702021Regulatory CDH4 Genetic Variants Associate With Risk to Develop Capecitabine-Induced Hand-Foot Syndrome.5
325112162020Expression and Prognostic Significance of Cadherin 4 (CDH4) in Renal Cell Carcinoma.4
325112162020Expression and Prognostic Significance of Cadherin 4 (CDH4) in Renal Cell Carcinoma.4
314265732019Cdh4 Down-Regulation Impairs in Vivo Infiltration and Malignancy in Patients Derived Glioblastoma Cells.12

Citation

Dessen P

CDH4 (cadherin 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40026/haematological-explorer/haematological-explorer/js/lib/bootstrap.min.js