CEACAM8 (CEA cell adhesion molecule 8)

2003-06-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
CD66b,CD67,CGM6,NCA-95

Other Information

Locus ID:

NCBI: 1088
MIM: 615747
HGNC: 1820
Ensembl: ENSG00000124469

Variants:

dbSNP: 1088
ClinVar: 1088
TCGA: ENSG00000124469
COSMIC: CEACAM8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124469ENST00000244336P31997
ENSG00000124469ENST00000244336Q0Z7S6
ENSG00000124469ENST00000599005M0R1X3

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Extracellular matrix organizationREACTOMER-HSA-1474244
Fibronectin matrix formationREACTOMER-HSA-1566977
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371626312023Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer.0
371626312023Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer.0
326326642021CD66b(+) monocytes represent a proinflammatory myeloid subpopulation in cancer.8
326326642021CD66b(+) monocytes represent a proinflammatory myeloid subpopulation in cancer.8
312226132019Co-expression of carcinoembryonic antigen-related cell adhesion molecule 6 and 8 inhibits proliferation and invasiveness of breast carcinoma cells.8
312226132019Co-expression of carcinoembryonic antigen-related cell adhesion molecule 6 and 8 inhibits proliferation and invasiveness of breast carcinoma cells.8
275798962016A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.5
278634782016Prognostic value of CD66b positive tumor-infiltrating neutrophils in testicular germ cell tumor.8
275798962016A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.5
278634782016Prognostic value of CD66b positive tumor-infiltrating neutrophils in testicular germ cell tumor.8
261766692015CD66b Overexpression and Loss of C5a Receptors as Surface Markers for Staphylococcus aureus-Induced Neutrophil Dysfunction.12
264834852015Diverse oligomeric states of CEACAM IgV domains.26
261766692015CD66b Overexpression and Loss of C5a Receptors as Surface Markers for Staphylococcus aureus-Induced Neutrophil Dysfunction.12
264834852015Diverse oligomeric states of CEACAM IgV domains.26
247433042014Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.26

Citation

Dessen P

CEACAM8 (CEA cell adhesion molecule 8)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40049/ceacam8