CETN1 (centrin 1)

2003-11-01  

Identity

HGNC
CETN1
LOCATION
18p11.32
LOCUSID
1068
ALIAS
CEN1,CETN

Other Information

Locus ID:

NCBI: 1068
MIM: 603187
HGNC: 1866
Ensembl: ENSG00000177143

Variants:

dbSNP: 1068
ClinVar: 1068
TCGA: ENSG00000177143
COSMIC: CETN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177143ENST00000327228Q12798
ENSG00000177143ENST00000327228A0A140VJG3

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
360488452023Exome sequencing and functional analyses revealed CETN1 variants leads to impaired cell division and male fertility.1
360488452023Exome sequencing and functional analyses revealed CETN1 variants leads to impaired cell division and male fertility.1
361251822022Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis.11
361251822022Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis.11
342736202021Conformational scanning of individual EF-hand motifs of calcium sensor protein centrin-1.1
342736202021Conformational scanning of individual EF-hand motifs of calcium sensor protein centrin-1.1
269238032016A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin.0
272351762016Optimization of purification method and characterization of recombinant human Centrin-1.1
269238032016A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin.0
272351762016Optimization of purification method and characterization of recombinant human Centrin-1.1
252616482014Knockdown of CETN1 inhibits breast cancer cells proliferation.2
252616482014Knockdown of CETN1 inhibits breast cancer cells proliferation.2
167604252006CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.53
167604252006CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.53

Citation

Dessen P

CETN1 (centrin 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40061