CHAF1A (chromatin assembly factor 1 subunit A)

2003-12-01  

Identity

HGNC
CHAF1A
LOCATION
19p13.3
LOCUSID
10036
ALIAS
CAF-1,CAF1,CAF1B,CAF1P150,P150
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10036
MIM: 601246
HGNC: 1910
Ensembl: ENSG00000167670

Variants:

dbSNP: 10036
ClinVar: 10036
TCGA: ENSG00000167670
COSMIC: CHAF1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167670ENST00000301280Q13111
ENSG00000167670ENST00000585371K7ENC7
ENSG00000167670ENST00000585854K7EJF1
ENSG00000167670ENST00000587739K7EPA1
ENSG00000167670ENST00000589648K7EME9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
346267732022DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC.4
350749172022CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.13
357737292022Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma.2
362323962022Unorthodox PCNA Binding by Chromatin Assembly Factor 1.4
346267732022DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC.4
350749172022CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.13
357737292022Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma.2
362323962022Unorthodox PCNA Binding by Chromatin Assembly Factor 1.4
330984902021Role of chromatin assembly factor-1/p60 and poly [ADP-ribose] polymerase 1 in mycosis fungoides.3
337858122021Identification and external validation of a prognostic signature associated with DNA repair genes in gastric cancer.3
342375852021Detection of CAF-1/p60 in peripheral blood as a potential biomarker of HNSCC tumors.2
343657422021CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.13
330984902021Role of chromatin assembly factor-1/p60 and poly [ADP-ribose] polymerase 1 in mycosis fungoides.3
337858122021Identification and external validation of a prognostic signature associated with DNA repair genes in gastric cancer.3
342375852021Detection of CAF-1/p60 in peripheral blood as a potential biomarker of HNSCC tumors.2

Citation

Dessen P

CHAF1A (chromatin assembly factor 1 subunit A)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40067/favicon/case-report-explorer/gene-fusions-explorer/