Identity
HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
ASRT7,CGP-39,GP-39,GP39,HC-gp39,HCGP-3P,YK-40,YKL-40,YKL40,YYL-40,hCGP-39
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1116
MIM: 601525
HGNC: 1932
Ensembl: ENSG00000133048
Variants:
dbSNP: 1116
ClinVar: 1116
TCGA: ENSG00000133048
COSMIC: CHI3L1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000133048 | ENST00000255409 | P36222 |
| ENSG00000133048 | ENST00000255409 | A0A024R969 |
| ENSG00000133048 | ENST00000404436 | H0Y3U8 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37690071 | 2024 | Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression. | 9 |
| 38159969 | 2024 | Clinical Significance of Chitinase-3-like Protein 1 Gene Expression in Patients With Locally Advanced Gastric Cancer. | 0 |
| 38290090 | 2024 | Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. | 0 |
| 38290591 | 2024 | TIMP1/CHI3L1 facilitates glioma progression and immunosuppression via NF-κB activation. | 2 |
| 38320988 | 2024 | A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1. | 1 |
| 38533556 | 2024 | YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability. | 0 |
| 38634621 | 2024 | YKL-40 Knockdown Decreases Oxidative Stress Damage in Ovarian Granulosa Cells. | 0 |
| 38667293 | 2024 | Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation. | 0 |
| 37690071 | 2024 | Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression. | 9 |
| 38159969 | 2024 | Clinical Significance of Chitinase-3-like Protein 1 Gene Expression in Patients With Locally Advanced Gastric Cancer. | 0 |
| 38290090 | 2024 | Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. | 0 |
| 38290591 | 2024 | TIMP1/CHI3L1 facilitates glioma progression and immunosuppression via NF-κB activation. | 2 |
| 38320988 | 2024 | A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1. | 1 |
| 38533556 | 2024 | YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability. | 0 |
| 38634621 | 2024 | YKL-40 Knockdown Decreases Oxidative Stress Damage in Ovarian Granulosa Cells. | 0 |
Citation
Dessen P
CHI3L1 (chitinase 3 like 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40075/chi3l1
