CKAP4 (cytoskeleton associated protein 4)

2003-02-01  

Identity

HGNC
LOCATION
12q23.3
LOCUSID
ALIAS
CLIMP-63,CLIMP63,ERGIC-63,p63
FUSION GENES

Other Information

Locus ID:

NCBI: 10970
MIM: 618595
HGNC: 16991
Ensembl: ENSG00000136026

Variants:

dbSNP: 10970
ClinVar: 10970
TCGA: ENSG00000136026
COSMIC: CKAP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136026ENST00000378026Q07065
ENSG00000136026ENST00000378026A0A024RBH2
ENSG00000136026ENST00000553039F8VVU0

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Metabolism of proteinsREACTOMER-HSA-392499
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Surfactant metabolismREACTOMER-HSA-5683826
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372089232023Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma.0
379163732023The clinical significance and diagnostic value of serum Dickkopf1 and CKAP4 levels in patients with gastric cancer: a prospective study.1
372089232023Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma.0
379163732023The clinical significance and diagnostic value of serum Dickkopf1 and CKAP4 levels in patients with gastric cancer: a prospective study.1
340790852021Plasmalemma vesicle-associated protein promotes angiogenesis in cholangiocarcinoma via the DKK1/CKAP4/PI3K signaling pathway.15
344700472021DKK1 activates noncanonical NF-κB signaling via IL-6-induced CKAP4 receptor in multiple myeloma.12
344766662021Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway.4
340790852021Plasmalemma vesicle-associated protein promotes angiogenesis in cholangiocarcinoma via the DKK1/CKAP4/PI3K signaling pathway.15
344700472021DKK1 activates noncanonical NF-κB signaling via IL-6-induced CKAP4 receptor in multiple myeloma.12
344766662021Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway.4
316965292020p63 overexpression in the epidermis of spiny keratoderma.0
325872552020The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.20
330672552020Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER-mitochondria contact sites.21
316965292020p63 overexpression in the epidermis of spiny keratoderma.0
325872552020The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.20

Citation

Dessen P

CKAP4 (cytoskeleton associated protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40088/meetings/gene-explorer/js/template.js