Identity
HGNC
LOCATION
1p22.3
LOCUSID
ALIAS
CACC,CACC3,CLCRG2,CaCC-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9635
MIM: 604003
HGNC: 2016
Ensembl: ENSG00000137975
Variants:
dbSNP: 9635
ClinVar: 9635
TCGA: ENSG00000137975
COSMIC: CLCA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137975 | ENST00000370565 | Q9UQC9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38528613 | 2024 | TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2. | 1 |
| 38602325 | 2024 | Transport of CLCA2 to the nucleus by extracellular vesicles controls keratinocyte survival and migration. | 1 |
| 38528613 | 2024 | TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2. | 1 |
| 38602325 | 2024 | Transport of CLCA2 to the nucleus by extracellular vesicles controls keratinocyte survival and migration. | 1 |
| 36280802 | 2022 | CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways. | 2 |
| 36280802 | 2022 | CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways. | 2 |
| 33966732 | 2021 | Decreased expression of CLCA2 and the correlating with immune infiltrates in patients with cervical squamous cell carcinoma: A bioinformatics analysis. | 3 |
| 33966732 | 2021 | Decreased expression of CLCA2 and the correlating with immune infiltrates in patients with cervical squamous cell carcinoma: A bioinformatics analysis. | 3 |
| 32131869 | 2020 | Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians. | 3 |
| 32298355 | 2020 | CLCA2 expression is associated with survival among African American women with triple negative breast cancer. | 6 |
| 32131869 | 2020 | Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians. | 3 |
| 32298355 | 2020 | CLCA2 expression is associated with survival among African American women with triple negative breast cancer. | 6 |
| 31326550 | 2019 | A newly identified missense mutation in CLCA2 is associated with autosomal dominant cardiac conduction block. | 6 |
| 31326550 | 2019 | A newly identified missense mutation in CLCA2 is associated with autosomal dominant cardiac conduction block. | 6 |
| 29463274 | 2018 | Along with its favorable prognostic role, CLCA2 inhibits growth and metastasis of nasopharyngeal carcinoma cells via inhibition of FAK/ERK signaling. | 26 |
Citation
Dessen P
CLCA2 (chloride channel accessory 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40096/clca2
