Identity
HGNC
LOCATION
4p16.2
LOCUSID
ALIAS
CRMP-1,DPYSL1,DRP-1,DRP1,ULIP-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1400
MIM: 602462
HGNC: 2365
Ensembl: ENSG00000072832
Variants:
dbSNP: 1400
ClinVar: 1400
TCGA: ENSG00000072832
COSMIC: CRMP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000072832 | ENST00000324989 | Q14194 |
| ENSG00000072832 | ENST00000324989 | X5DNI1 |
| ENSG00000072832 | ENST00000397890 | Q14194 |
| ENSG00000072832 | ENST00000512574 | E9PD68 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| Semaphorin interactions | REACTOME | R-HSA-373755 |
| CRMPs in Sema3A signaling | REACTOME | R-HSA-399956 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36511780 | 2022 | Monoallelic CRMP1 gene variants cause neurodevelopmental disorder. | 4 |
| 36511780 | 2022 | Monoallelic CRMP1 gene variants cause neurodevelopmental disorder. | 4 |
| 30466368 | 2019 | Overexpression of Collapsin Response Mediator Protein 1 Inhibits Human Trophoblast Cells Proliferation, Migration, and Invasion. | 2 |
| 30466368 | 2019 | Overexpression of Collapsin Response Mediator Protein 1 Inhibits Human Trophoblast Cells Proliferation, Migration, and Invasion. | 2 |
| 29666369 | 2018 | Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder. | 9 |
| 29666369 | 2018 | Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder. | 9 |
| 27321179 | 2017 | Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial-mesenchymal transition and remodeling of actin cytoskeleton organization. | 24 |
| 27864146 | 2017 | MicroRNA-187 regulates gastric cancer progression by targeting the tumor suppressor CRMP1. | 6 |
| 28630144 | 2017 | CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex. | 12 |
| 27321179 | 2017 | Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial-mesenchymal transition and remodeling of actin cytoskeleton organization. | 24 |
| 27864146 | 2017 | MicroRNA-187 regulates gastric cancer progression by targeting the tumor suppressor CRMP1. | 6 |
| 28630144 | 2017 | CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex. | 12 |
| 25526860 | 2016 | CRMP1 Interacted with Spy1 During the Collapse of Growth Cones Induced by Sema3A and Acted on Regeneration After Sciatic Nerve Crush. | 9 |
| 26598519 | 2016 | Collapsin Response Mediator Protein-1 Regulates Arp2/3-dependent Actin Assembly. | 7 |
| 28025999 | 2016 | miR-200a-3p promotes the proliferation of human esophageal cancer cells by post-transcriptionally regulating cytoplasmic collapsin response mediator protein-1. | 12 |
Citation
Dessen P
CRMP1 (collapsin response mediator protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40151/crmp1
