Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1408
MIM: 603732
HGNC: 2385
Ensembl: ENSG00000121671
Variants:
dbSNP: 1408
ClinVar: 1408
TCGA: ENSG00000121671
COSMIC: CRY2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Circadian rhythm | KEGG | ko04710 |
| Circadian rhythm | KEGG | hsa04710 |
| Circadian Clock | REACTOME | R-HSA-400253 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | REACTOME | R-HSA-1368108 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38537935 | 2024 | Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion. | 0 |
| 38537935 | 2024 | Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion. | 0 |
| 37724597 | 2023 | Transcription Repression of CRY2 via PER2 Interaction Promotes Adipogenesis. | 1 |
| 37951306 | 2023 | Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2. | 0 |
| 37724597 | 2023 | Transcription Repression of CRY2 via PER2 Interaction Promotes Adipogenesis. | 1 |
| 37951306 | 2023 | Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2. | 0 |
| 34732337 | 2022 | Alterations in CRY2 and PER3 gene expression associated with thalamic-limbic community structural abnormalities in patients with bipolar depression or unipolar depression. | 2 |
| 35088238 | 2022 | Knockdown of UCHL3 inhibits esophageal squamous cell carcinoma progression by reducing CRY2 methylation. | 4 |
| 35933018 | 2022 | The secondary pocket of cryptochrome 2 is important for the regulation of its stability and localization. | 1 |
| 34732337 | 2022 | Alterations in CRY2 and PER3 gene expression associated with thalamic-limbic community structural abnormalities in patients with bipolar depression or unipolar depression. | 2 |
| 35088238 | 2022 | Knockdown of UCHL3 inhibits esophageal squamous cell carcinoma progression by reducing CRY2 methylation. | 4 |
| 35933018 | 2022 | The secondary pocket of cryptochrome 2 is important for the regulation of its stability and localization. | 1 |
| 32776544 | 2021 | MALAT1 recruited the E3 ubiquitin ligase FBXW7 to induce CRY2 ubiquitin-mediated degradation and participated in trophoblast migration and invasion. | 5 |
| 33629313 | 2021 | SPRR2C, DEFB4A, WIF1, CRY2, and KRT19 are correlated with the development of atopic eczema. | 0 |
| 33709300 | 2021 | Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B. | 2 |
Citation
Dessen P
CRY2 (cryptochrome circadian regulator 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40155/cry2
