CST3 (cystatin C)

2003-08-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
ARMD11,HEL-S-2
FUSION GENES

Other Information

Locus ID:

NCBI: 1471
MIM: 604312
HGNC: 2475
Ensembl: ENSG00000101439

Variants:

dbSNP: 1471
ClinVar: 1471
TCGA: ENSG00000101439
COSMIC: CST3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101439ENST00000376925P01034
ENSG00000101439ENST00000376925A0A0K0K1J1
ENSG00000101439ENST00000398409P01034
ENSG00000101439ENST00000398409A0A0K0K1J1
ENSG00000101439ENST00000398411P01034
ENSG00000101439ENST00000398411A0A0K0K1J1

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Metabolism of proteinsREACTOMER-HSA-392499
Amyloid fiber formationREACTOMER-HSA-977225
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375487572024Serum Cystatin C is a potential biomarker for predicting amyotrophic lateral sclerosis survival.2
378667932024Modification of Association of Cystatin C With Kidney and Cardiovascular Outcomes by Obesity.0
381256202024Determination of cystatin C reference interval for children in Croatia.0
387083452024Cystatin C: immunoregulation role in macrophages infected with Porphyromonas gingivalis.0
375487572024Serum Cystatin C is a potential biomarker for predicting amyotrophic lateral sclerosis survival.2
378667932024Modification of Association of Cystatin C With Kidney and Cardiovascular Outcomes by Obesity.0
381256202024Determination of cystatin C reference interval for children in Croatia.0
387083452024Cystatin C: immunoregulation role in macrophages infected with Porphyromonas gingivalis.0
363271582023Does cystatin C have an immunomodulatory role in Hashimoto's thyroiditis?1
364029312023Mast cells inhibit colorectal cancer development by inducing ER stress through secreting Cystatin C.7
364843722023Coronary artery calcium and cystatin C for risk stratification of MACCEs and all-cause death in symptomatic patients.1
365458372023Lower serum cystatin C level predicts poor functional outcome in patients with hypertensive intracerebral hemorrhage independent of renal function.1
366374592023Using Serum Cystatin C to Predict Acute Kidney Injury Following Infant Cardiac Surgery.2
367241532023Cystatin C proteoforms in chronic kidney disease.2
370388172023Association Between Serum Cystatin C and Cognitive Decline Independently from Creatinine: Evidence from Two Nationally Representative Aging Cohorts.1

Citation

Dessen P

CST3 (cystatin C)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40177/cst3