CSTF1 (cleavage stimulation factor subunit 1)

2003-02-01  

Identity

HGNC
CSTF1
LOCATION
20q13.2
LOCUSID
1477
ALIAS
CstF-50,CstFp50
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1477
MIM: 600369
HGNC: 2483
Ensembl: ENSG00000101138

Variants:

dbSNP: 1477
ClinVar: 1477
TCGA: ENSG00000101138
COSMIC: CSTF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101138ENST00000217109Q05048
ENSG00000101138ENST00000415828A0A0A0MSZ9
ENSG00000101138ENST00000428552A3KFI9
ENSG00000101138ENST00000452950A0A0A0MSZ9
ENSG00000101138ENST00000490539A0A087WV92
ENSG00000101138ENST00000493039A0A087WV92

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Processing of Capped Intronless Pre-mRNAREACTOMER-HSA-75067
Processing of Intronless Pre-mRNAsREACTOMER-HSA-77595

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.27
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.11
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.17
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.27
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.11
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.17
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.36
188420002008The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.19
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.36
188420002008The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.19
158782322006A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.7

Citation

Dessen P

CSTF1 (cleavage stimulation factor subunit 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40182/css/deep-insight-explorer/gene-fusions-explorer/