Identity
HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
CTS02,CTSO,CTSO1,CTSO2,PKND,PYCD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1513
MIM: 601105
HGNC: 2536
Ensembl: ENSG00000143387
Variants:
dbSNP: 1513
ClinVar: 1513
TCGA: ENSG00000143387
COSMIC: CTSK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143387 | ENST00000271651 | P43235 |
| ENSG00000143387 | ENST00000443913 | Q5QP40 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38703204 | 2024 | Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeCl(3) model. | 0 |
| 38703204 | 2024 | Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeCl(3) model. | 0 |
| 36697252 | 2023 | Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen. | 1 |
| 37938323 | 2023 | mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy. | 1 |
| 36697252 | 2023 | Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen. | 1 |
| 37938323 | 2023 | mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy. | 1 |
| 34433182 | 2022 | Cathepsin K is Superior to HMB45 for the Diagnosis of Pulmonary Lymphangioleiomyomatosis. | 1 |
| 35315254 | 2022 | Clinical and genetic characterization of three Russian patients with pycnodysostosis due to pathogenic variants in the CTSK gene. | 4 |
| 36138018 | 2022 | Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer. | 16 |
| 34433182 | 2022 | Cathepsin K is Superior to HMB45 for the Diagnosis of Pulmonary Lymphangioleiomyomatosis. | 1 |
| 35315254 | 2022 | Clinical and genetic characterization of three Russian patients with pycnodysostosis due to pathogenic variants in the CTSK gene. | 4 |
| 36138018 | 2022 | Cathepsin K regulates the tumor growth and metastasis by IL-17/CTSK/EMT axis and mediates M2 macrophage polarization in castration-resistant prostate cancer. | 16 |
| 33227497 | 2021 | Human cathepsin X/Z is a biologically active homodimer. | 6 |
| 33429075 | 2021 | Clinical and genetic evaluation of Danish patients with pycnodysostosis. | 8 |
| 33445732 | 2021 | Elevated Expression of Cathepsin K in Periodontal Ligament Fibroblast by Inflammatory Cytokines Accelerates Osteoclastogenesis via Paracrine Mechanism in Periodontal Disease. | 4 |
Citation
Dessen P
CTSK (cathepsin K)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40207/ctsk
