CYB561 (cytochrome b561)

2003-05-01  

Identity

HGNC
CYB561
LOCATION
17q23.3
LOCUSID
1534
ALIAS
CYB561A1,FRRS2,ORTHYP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1534
MIM: 600019
HGNC: 2571
Ensembl: ENSG00000008283

Variants:

dbSNP: 1534
ClinVar: 1534
TCGA: ENSG00000008283
COSMIC: CYB561

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008283ENST00000360793P49447
ENSG00000008283ENST00000392975P49447
ENSG00000008283ENST00000392976P49447
ENSG00000008283ENST00000448884P49447
ENSG00000008283ENST00000542042F5H757
ENSG00000008283ENST00000578072J3QRF9
ENSG00000008283ENST00000580592J3QLS0
ENSG00000008283ENST00000580691J3KSL5
ENSG00000008283ENST00000581573P49447
ENSG00000008283ENST00000582034J3QS47
ENSG00000008283ENST00000582297J3QS09
ENSG00000008283ENST00000582997J3QRH5
ENSG00000008283ENST00000584031J3QKN3
ENSG00000008283ENST00000584291P49447
ENSG00000008283ENST00000585153J3QR25

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375842872024miR-30e-5p regulates leukemia stem cell self-renewal through the Cyb561/ROS signaling pathway.1
375842872024miR-30e-5p regulates leukemia stem cell self-renewal through the Cyb561/ROS signaling pathway.1
376345622023Cytochrome b561 regulates iron metabolism by activating the Akt/mTOR pathway to promote Breast Cancer Cells proliferation.0
380393242023Comparison of insect and human cytochrome b561 proteins: Insights into candidate ferric reductases in insects.1
376345622023Cytochrome b561 regulates iron metabolism by activating the Akt/mTOR pathway to promote Breast Cancer Cells proliferation.0
380393242023Comparison of insect and human cytochrome b561 proteins: Insights into candidate ferric reductases in insects.1
293435262018Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome.9
293435262018Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome.9
241406602014Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].6
241406602014Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected].6
206803102010Nucleotide variations in mitochondrial DNA and supra-physiological ROS levels in cytogenetically normal cases of premature ovarian insufficiency.15
206803102010Nucleotide variations in mitochondrial DNA and supra-physiological ROS levels in cytogenetically normal cases of premature ovarian insufficiency.15
181803942008Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans.7
181803942008Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans.7
127683392003Structure prediction for the di-heme cytochrome b561 protein family.11

Citation

Dessen P

CYB561 (cytochrome b561)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40228/css/js/js/template.js