Identity
HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
DDBA,UV-DDB1,XAP1,XPCE,XPE,XPE-BF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1642
MIM: 600045
HGNC: 2717
Ensembl: ENSG00000167986
Variants:
dbSNP: 1642
ClinVar: 1642
TCGA: ENSG00000167986
COSMIC: DDB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38934719 | 2024 | Hepatocyte-specific loss of DDB1 attenuates hepatic steatosis but aggravates liver inflammation and fibrosis in MASH. | 0 |
| 38934719 | 2024 | Hepatocyte-specific loss of DDB1 attenuates hepatic steatosis but aggravates liver inflammation and fibrosis in MASH. | 0 |
| 37043057 | 2023 | DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7. | 1 |
| 37043057 | 2023 | DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7. | 1 |
| 34705558 | 2022 | Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation. | 8 |
| 35938868 | 2022 | Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex. | 1 |
| 34705558 | 2022 | Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation. | 8 |
| 35938868 | 2022 | Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex. | 1 |
| 33743206 | 2021 | A DNA repair disorder caused by de novo monoallelic DDB1 variants is associated with a neurodevelopmental syndrome. | 2 |
| 34373747 | 2021 | HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver. | 13 |
| 34720086 | 2021 | Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine. | 27 |
| 33743206 | 2021 | A DNA repair disorder caused by de novo monoallelic DDB1 variants is associated with a neurodevelopmental syndrome. | 2 |
| 34373747 | 2021 | HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver. | 13 |
| 34720086 | 2021 | Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine. | 27 |
| 32235678 | 2020 | Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex. | 18 |
Citation
Dessen P
DDB1 (damage specific DNA binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40278/ddb1
