DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
2003-02-01 AffiliationIdentity
HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
AGER1,CDG1R,GATD6,OKSWcl45,OST,OST48,WBP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1650
MIM: 602202
HGNC: 2728
Ensembl: ENSG00000244038
Variants:
dbSNP: 1650
ClinVar: 1650
TCGA: ENSG00000244038
COSMIC: DDOST
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000244038 | ENST00000375048 | P39656 |
| ENSG00000244038 | ENST00000415136 | P39656 |
| ENSG00000244038 | ENST00000464364 | U3KQ84 |
| ENSG00000244038 | ENST00000602624 | A0A0C4DGS1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37848450 | 2023 | Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation. | 1 |
| 38139276 | 2023 | AGER-1 Long Non-Coding RNA Levels Correlate with the Expression of the Advanced Glycosylation End-Product Receptor, a Regulator of the Inflammatory Response in Visceral Adipose Tissue of Women with Obesity and Type 2 Diabetes Mellitus. | 0 |
| 37848450 | 2023 | Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation. | 1 |
| 38139276 | 2023 | AGER-1 Long Non-Coding RNA Levels Correlate with the Expression of the Advanced Glycosylation End-Product Receptor, a Regulator of the Inflammatory Response in Visceral Adipose Tissue of Women with Obesity and Type 2 Diabetes Mellitus. | 0 |
| 35269546 | 2022 | Advanced Glycation End Products: A Sweet Flavor That Embitters Cardiovascular Disease. | 7 |
| 35269546 | 2022 | Advanced Glycation End Products: A Sweet Flavor That Embitters Cardiovascular Disease. | 7 |
| 31810196 | 2019 | Oligosaccharyltransferase: A Gatekeeper of Health and Tumor Progression. | 30 |
| 31810196 | 2019 | Oligosaccharyltransferase: A Gatekeeper of Health and Tumor Progression. | 30 |
| 29027826 | 2018 | Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients. | 9 |
| 29027826 | 2018 | Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients. | 9 |
| 28297665 | 2017 | Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex. | 11 |
| 28947796 | 2017 | Increased liver AGEs induce hepatic injury mediated through an OST48 pathway. | 13 |
| 28297665 | 2017 | Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex. | 11 |
| 28947796 | 2017 | Increased liver AGEs induce hepatic injury mediated through an OST48 pathway. | 13 |
| 22305527 | 2012 | DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation. | 35 |
Citation
Dessen P
DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40279/ddost
