DDX53 (DEAD-box helicase 53)

2003-06-01  

Identity

HGNC
DDX53
LOCATION
Xp22.11
LOCUSID
168400
ALIAS
CAGE,CT26
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 168400
HGNC: 20083
Ensembl: ENSG00000184735

Variants:

dbSNP: 168400
ClinVar: 168400
TCGA: ENSG00000184735
COSMIC: DDX53

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184735ENST00000327968Q86TM3

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
366356622023Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.3
366356622023Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.3
304547002018Role of DDX53 in taxol-resistance of cervix cancer cells in vitro.8
304547002018Role of DDX53 in taxol-resistance of cervix cancer cells in vitro.8
281522972017DDX53 Promotes Cancer Stem Cell-Like Properties and Autophagy.17
285356662017DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2.12
281522972017DDX53 Promotes Cancer Stem Cell-Like Properties and Autophagy.17
285356662017DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2.12
268636292016miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2.12
268839072016Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs.9
269120822016miR-30a Regulates the Expression of CAGE and p53 and Regulates the Response to Anti-Cancer Drugs.10
268636292016miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2.12
268839072016Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs.9
269120822016miR-30a Regulates the Expression of CAGE and p53 and Regulates the Response to Anti-Cancer Drugs.10
205314692010Functional impact of global rare copy number variation in autism spectrum disorders.980

Citation

Dessen P

DDX53 (DEAD-box helicase 53)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40291