Identity
HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
MRX,MRX90,NEDLG,PPP1R82,SAP102,XLMR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1741
MIM: 300189
HGNC: 2902
Ensembl: ENSG00000082458
Variants:
dbSNP: 1741
ClinVar: 1741
TCGA: ENSG00000082458
COSMIC: DLG3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000082458 | ENST00000194900 | Q5JUW8 |
| ENSG00000082458 | ENST00000374355 | Q92796 |
| ENSG00000082458 | ENST00000374360 | Q92796 |
| ENSG00000082458 | ENST00000542398 | Q92796 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38273165 | 2024 | Identification of a DLG3 stop mutation in the MRX20 family. | 1 |
| 38273165 | 2024 | Identification of a DLG3 stop mutation in the MRX20 family. | 1 |
| 32593652 | 2020 | Silence of lncRNA MIAT-mediated inhibition of DLG3 promoter methylation suppresses breast cancer progression via the Hippo signaling pathway. | 18 |
| 32593652 | 2020 | Silence of lncRNA MIAT-mediated inhibition of DLG3 promoter methylation suppresses breast cancer progression via the Hippo signaling pathway. | 18 |
| 31271664 | 2019 | High expression of DLG3 is associated with decreased survival from breast cancer. | 8 |
| 31271664 | 2019 | High expression of DLG3 is associated with decreased survival from breast cancer. | 8 |
| 29282697 | 2018 | Regulation of SAP102 Synaptic Targeting by Phosphorylation. | 9 |
| 29282697 | 2018 | Regulation of SAP102 Synaptic Targeting by Phosphorylation. | 9 |
| 28777483 | 2017 | Skewed X-inactivation in a family with DLG3-associated X-linked intellectual disability. | 5 |
| 28777483 | 2017 | Skewed X-inactivation in a family with DLG3-associated X-linked intellectual disability. | 5 |
| 27222290 | 2016 | A non-coding variant in the 5' UTR of DLG3 attenuates protein translation to cause non-syndromic intellectual disability. | 3 |
| 27222290 | 2016 | A non-coding variant in the 5' UTR of DLG3 attenuates protein translation to cause non-syndromic intellectual disability. | 3 |
| 27466188 | 2016 | Altered thalamocortical development in the SAP102 knockout model of intellectual disability. | 7 |
| 27222290 | 2016 | A non-coding variant in the 5' UTR of DLG3 attenuates protein translation to cause non-syndromic intellectual disability. | 3 |
| 27222290 | 2016 | A non-coding variant in the 5' UTR of DLG3 attenuates protein translation to cause non-syndromic intellectual disability. | 3 |
Citation
Dessen P
DLG3 (discs large MAGUK scaffold protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40334/dlg3
