DMP1 (dentin matrix acidic phosphoprotein 1)

2003-05-01  

Identity

HGNC
DMP1
LOCATION
4q22.1
LOCUSID
1758
ALIAS
ARHP,ARHR,DMP-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1758
MIM: 600980
HGNC: 2932
Ensembl: ENSG00000152592

Variants:

dbSNP: 1758
ClinVar: 1758
TCGA: ENSG00000152592
COSMIC: DMP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152592ENST00000282479Q13316
ENSG00000152592ENST00000339673Q13316

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
363159082023First report in Argentina of a pathogenic DMP1 variant associated with autosomal recessive hypophosphatemic rickets.0
363159082023First report in Argentina of a pathogenic DMP1 variant associated with autosomal recessive hypophosphatemic rickets.0
359816982022Mettl3 regulates hypertrophic differentiation of chondrocytes through modulating Dmp1 mRNA via Ythdf1-mediated m(6)A modification.2
364824082022Whole exome sequencing identifies two novel variants in PHEX and DMP1 in Malaysian children with hypophosphatemic rickets.1
359816982022Mettl3 regulates hypertrophic differentiation of chondrocytes through modulating Dmp1 mRNA via Ythdf1-mediated m(6)A modification.2
364824082022Whole exome sequencing identifies two novel variants in PHEX and DMP1 in Malaysian children with hypophosphatemic rickets.1
334208982021DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration.8
334208982021DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration.8
292787082018Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma.5
292897092018Periostin, dentin matrix protein 1 and P2rx7 ion channel in human teeth and periodontal ligament.4
292787082018Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma.5
292897092018Periostin, dentin matrix protein 1 and P2rx7 ion channel in human teeth and periodontal ligament.4
282470292017In focus in HCB.0
282470292017In focus in HCB.0
256780292016Immunolocalization of dentin matrix protein-1 in human primary teeth treated with different pulp capping materials.12

Citation

Dessen P

DMP1 (dentin matrix acidic phosphoprotein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40338/gene-fusions-explorer/favicon/js/template.js