Identity
HGNC
LOCATION
9p21.1
LOCUSID
ALIAS
DJ-2,DjA1,HDJ2,HSDJ,HSJ-2,HSJ2,HSPF4,NEDD7,hDJ-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3301
MIM: 602837
HGNC: 5229
Ensembl: ENSG00000086061
Variants:
dbSNP: 3301
ClinVar: 3301
TCGA: ENSG00000086061
COSMIC: DNAJA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000086061 | ENST00000330899 | P31689 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38309209 | 2024 | Novel insights into the post-translational modifications of Ydj1/DNAJA1 co-chaperones. | 2 |
| 38309209 | 2024 | Novel insights into the post-translational modifications of Ydj1/DNAJA1 co-chaperones. | 2 |
| 37977037 | 2023 | DNAJA1 promotes proliferation and metastasis of breast cancer by activating mutant P53/NF-κB pathway. | 0 |
| 37977037 | 2023 | DNAJA1 promotes proliferation and metastasis of breast cancer by activating mutant P53/NF-κB pathway. | 0 |
| 36291603 | 2022 | Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies. | 0 |
| 36291603 | 2022 | Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies. | 0 |
| 33208462 | 2021 | Identification of a druggable protein-protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1. | 13 |
| 33972400 | 2021 | Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1. | 3 |
| 34183772 | 2021 | DNAJA1 promotes cancer metastasis through interaction with mutant p53. | 11 |
| 34236236 | 2021 | High expression of DNAJA1 (HDJ2) predicts unfavorable survival outcomes in breast cancer. | 3 |
| 34264680 | 2021 | DNAJA1 Dysregulates Metabolism Promoting an Antiapoptotic Phenotype in Pancreatic Ductal Adenocarcinoma. | 3 |
| 33208462 | 2021 | Identification of a druggable protein-protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1. | 13 |
| 33972400 | 2021 | Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1. | 3 |
| 34183772 | 2021 | DNAJA1 promotes cancer metastasis through interaction with mutant p53. | 11 |
| 34236236 | 2021 | High expression of DNAJA1 (HDJ2) predicts unfavorable survival outcomes in breast cancer. | 3 |
Citation
Dessen P
DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40341/dnaja1
