DNTT (DNA nucleotidylexotransferase)

2003-12-01  

Identity

HGNC
DNTT
LOCATION
10q24.1
LOCUSID
1791
ALIAS
TDT

Other Information

Locus ID:

NCBI: 1791
MIM: 187410
HGNC: 2983
Ensembl: ENSG00000107447

Variants:

dbSNP: 1791
ClinVar: 1791
TCGA: ENSG00000107447
COSMIC: DNTT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107447ENST00000371174P04053
ENSG00000107447ENST00000630152P04053

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Non-homologous end-joiningKEGGko03450
Hematopoietic cell lineageKEGGko04640
Non-homologous end-joiningKEGGhsa03450
Hematopoietic cell lineageKEGGhsa04640

References

Pubmed IDYearTitleCitations
385795762024Terminal deoxynucleotidyl transferase expression in different subtypes of childhood B-cell acute lymphoblastic leukemia.0
385795762024Terminal deoxynucleotidyl transferase expression in different subtypes of childhood B-cell acute lymphoblastic leukemia.0
378585442023DNA strand displacement and TdT-Mediated DNA extension for swift, convenient, and quantitative evaluation of sperm DNA integrity and its clinical implications.0
378585442023DNA strand displacement and TdT-Mediated DNA extension for swift, convenient, and quantitative evaluation of sperm DNA integrity and its clinical implications.0
322536652020Prognostic implications of TdT expression in acute myeloid leukemia with an intermediate-risk karyotype.1
330916162020Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia.3
322536652020Prognostic implications of TdT expression in acute myeloid leukemia with an intermediate-risk karyotype.1
330916162020Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia.3
316501622019Molecular roulette: nucleophosmin mutations in AML are orchestrated through N-nucleotide addition by TdT.12
316501682019Terminal deoxynucleotidyl transferase promotes acute myeloid leukemia by priming FLT3-ITD replication slippage.8
316501622019Molecular roulette: nucleophosmin mutations in AML are orchestrated through N-nucleotide addition by TdT.12
316501682019Terminal deoxynucleotidyl transferase promotes acute myeloid leukemia by priming FLT3-ITD replication slippage.8
282488162017TdT-positive Infiltrate in Inflamed Pediatric Kidney: A Potential Diagnostic Pitfall.1
286772992017TdT expression in normal and neoplastic sebaceous cells.2
291870452017Terminal Deoxynucleotidyl Transferase (TdT)-negative Lymphoblastic Leukemia in Pediatric Patients: Incidence and Clinical Significance.4

Citation

Dessen P

DNTT (DNA nucleotidylexotransferase)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40351