Identity
HGNC
LOCATION
18q12.1
LOCUSID
ALIAS
CDHF3,DSC,DSC1,DSC2,DSC4,HT-CP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1825
MIM: 600271
HGNC: 3037
Ensembl: ENSG00000134762
Variants:
dbSNP: 1825
ClinVar: 1825
TCGA: ENSG00000134762
COSMIC: DSC3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134762 | ENST00000360428 | Q14574 |
| ENSG00000134762 | ENST00000434452 | Q14574 |
| ENSG00000134762 | ENST00000584980 | J3QRL9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36305887 | 2023 | Two cases of Hallopeau-type pemphigus vegetans with anti-desmoglein 1 and anti-desmocollin 3 antibodies without mucosal involvement. | 0 |
| 38651843 | 2023 | Upregulation of Anti-Desmocollin 3 Antibodies in Pemphigus Diseases: A Case-control Study. | 0 |
| 36305887 | 2023 | Two cases of Hallopeau-type pemphigus vegetans with anti-desmoglein 1 and anti-desmocollin 3 antibodies without mucosal involvement. | 0 |
| 38651843 | 2023 | Upregulation of Anti-Desmocollin 3 Antibodies in Pemphigus Diseases: A Case-control Study. | 0 |
| 33766509 | 2021 | Autoantibodies to DSC3 in Pemphigus Exclusively Recognize Calcium-Dependent Epitope in Extracellular Domain 2. | 2 |
| 33766509 | 2021 | Autoantibodies to DSC3 in Pemphigus Exclusively Recognize Calcium-Dependent Epitope in Extracellular Domain 2. | 2 |
| 30857973 | 2019 | Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer. | 9 |
| 30857973 | 2019 | Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer. | 9 |
| 28094105 | 2017 | Sonographic alteration of substantia nigra is related to parkinsonism-predominant course of X-linked dystonia-parkinsonism. | 5 |
| 28154962 | 2017 | Expression of Desmoglein 2, Desmocollin 3 and Plakophilin 2 in Placenta and Bone Marrow-Derived Mesenchymal Stromal Cells. | 2 |
| 28094105 | 2017 | Sonographic alteration of substantia nigra is related to parkinsonism-predominant course of X-linked dystonia-parkinsonism. | 5 |
| 28154962 | 2017 | Expression of Desmoglein 2, Desmocollin 3 and Plakophilin 2 in Placenta and Bone Marrow-Derived Mesenchymal Stromal Cells. | 2 |
| 26710975 | 2016 | The role of Napsin-A and Desmocollin-3 in classifying poorly differentiating non-small cell lung carcinoma. | 2 |
| 26710975 | 2016 | The role of Napsin-A and Desmocollin-3 in classifying poorly differentiating non-small cell lung carcinoma. | 2 |
| 26261554 | 2015 | Desmocollin 3 mediates follicle stimulating hormone-induced ovarian epithelial cancer cell proliferation by activating the EGFR/Akt signaling pathway. | 5 |
Citation
Dessen P
DSC3 (desmocollin 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40364/dsc3
