DSPP (dentin sialophosphoprotein)

2003-05-01  

Identity

HGNC
DSPP
LOCATION
4q22.1
LOCUSID
1834
ALIAS
DFNA39,DGI1,DMP3,DPP,DSP

Other Information

Locus ID:

NCBI: 1834
MIM: 125485
HGNC: 3054
Ensembl: ENSG00000152591

Variants:

dbSNP: 1834
ClinVar: 1834
TCGA: ENSG00000152591
COSMIC: DSPP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152591ENST00000651931Q9NZW4

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
385465162024The Role of DSPP in Dentine Formation and Hereditary Dentine Defects.1
386303282024Isolated dentinogenesis imperfecta: Novel DSPP variants and insights on genetic counselling.0
385465162024The Role of DSPP in Dentine Formation and Hereditary Dentine Defects.1
386303282024Isolated dentinogenesis imperfecta: Novel DSPP variants and insights on genetic counselling.0
365976172023A novel DSPP frameshift mutation causing dentin dysplasia type 2 and disease management strategies.0
366424482023[Mutation of dentin sialophosphoprotein and hereditary malformations of dentin].1
370177522023Identification of DSPP novel variants and phenotype analysis in dentinogenesis dysplasia Shields type II patients.1
370844842023Novel dentin sialophosphoprotein gene frameshift mutations affect dentin mineralization.1
365976172023A novel DSPP frameshift mutation causing dentin dysplasia type 2 and disease management strategies.0
366424482023[Mutation of dentin sialophosphoprotein and hereditary malformations of dentin].1
370177522023Identification of DSPP novel variants and phenotype analysis in dentinogenesis dysplasia Shields type II patients.1
370844842023Novel dentin sialophosphoprotein gene frameshift mutations affect dentin mineralization.1
346672132021Mouse Dspp frameshift model of human dentinogenesis imperfecta.6
346672132021Mouse Dspp frameshift model of human dentinogenesis imperfecta.6
309323692019Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.6

Citation

Dessen P

DSPP (dentin sialophosphoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40368/js/lib/css/lib/favicon/manifest.json