Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8270
MIM: 300060
HGNC: 26058
Ensembl: ENSG00000196976
Variants:
dbSNP: 8270
ClinVar: 8270
TCGA: ENSG00000196976
COSMIC: LAGE3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196976 | ENST00000357360 | Q14657 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37473499 | 2023 | LAGE3 promotes cell metastasis and stemness in non-small cell lung cancer companied with AKT/PI3K signaling pathway activation. | 0 |
| 37473499 | 2023 | LAGE3 promotes cell metastasis and stemness in non-small cell lung cancer companied with AKT/PI3K signaling pathway activation. | 0 |
| 33310661 | 2021 | Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer. | 8 |
| 34837962 | 2021 | LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway. | 11 |
| 33310661 | 2021 | Identification and validation of L Antigen Family Member 3 as an immune-related biomarker associated with the progression of papillary thyroid cancer. | 8 |
| 34837962 | 2021 | LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway. | 11 |
| 32438075 | 2020 | Upregulation of LAGE3 correlates with prognosis and immune infiltrates in colorectal cancer: A bioinformatic analysis. | 13 |
| 32683301 | 2020 | LAGE3 correlates with tumorigenic immune infiltrates in the clear cell renal cell carcinoma microenvironment. | 11 |
| 32945386 | 2020 | lncRNA NEAT1 regulates the proliferation and migration of hepatocellular carcinoma cells by acting as a miR‑320a molecular sponge and targeting L antigen family member 3. | 8 |
| 32438075 | 2020 | Upregulation of LAGE3 correlates with prognosis and immune infiltrates in colorectal cancer: A bioinformatic analysis. | 13 |
| 32683301 | 2020 | LAGE3 correlates with tumorigenic immune infiltrates in the clear cell renal cell carcinoma microenvironment. | 11 |
| 32945386 | 2020 | lncRNA NEAT1 regulates the proliferation and migration of hepatocellular carcinoma cells by acting as a miR‑320a molecular sponge and targeting L antigen family member 3. | 8 |
Citation
Dessen P
LAGE3 (L antigen family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40380/lage3
