E4F1 (E4F transcription factor 1)

2003-02-01  

Identity

HGNC
E4F1
LOCATION
16p13.3
LOCUSID
1877
ALIAS
E4F
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1877
MIM: 603022
HGNC: 3121
Ensembl: ENSG00000167967

Variants:

dbSNP: 1877
ClinVar: 1877
TCGA: ENSG00000167967
COSMIC: E4F1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167967ENST00000301727Q66K89
ENSG00000167967ENST00000562589H3BQZ4
ENSG00000167967ENST00000564139H3BUJ7
ENSG00000167967ENST00000565090H3BSL4
ENSG00000167967ENST00000565413H3BN24

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377740362023Transcription factor E4F1 as a regulator of cell life and disease progression.1
377740362023Transcription factor E4F1 as a regulator of cell life and disease progression.1
360124782022Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer.1
360124782022Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer.1
336921242021Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.14
348577602021The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.10
336921242021Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.14
348577602021The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.10
305066472019E4F1 silencing inhibits the cell growth through cell-cycle arrest in malignant transformed cells induced by hydroquinone.6
305066472019E4F1 silencing inhibits the cell growth through cell-cycle arrest in malignant transformed cells induced by hydroquinone.6
269688972016New genes and pathomechanisms in mitochondrial disorders unraveled by NGS technologies.52
269688972016New genes and pathomechanisms in mitochondrial disorders unraveled by NGS technologies.52
241634012014Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism.7
241634012014Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism.7
217089272011E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.16

Citation

Dessen P

E4F1 (E4F transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40389/meetings/gene-fusions-explorer/gene-explorer/