Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
EEF-2,EF-2,EF2,SCA26
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1938
MIM: 130610
HGNC: 3214
Ensembl: ENSG00000167658
Variants:
dbSNP: 1938
ClinVar: 1938
TCGA: ENSG00000167658
COSMIC: EEF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167658 | ENST00000309311 | P13639 |
| ENSG00000167658 | ENST00000309311 | A0A384N6H1 |
| ENSG00000167658 | ENST00000600794 | M0R0I6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36520140 | 2023 | Identification of a novel recurrent EEF2 gene amplification in familial prostate tumors. | 1 |
| 37084140 | 2023 | eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration. | 6 |
| 37209825 | 2023 | The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation. | 2 |
| 36520140 | 2023 | Identification of a novel recurrent EEF2 gene amplification in familial prostate tumors. | 1 |
| 37084140 | 2023 | eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration. | 6 |
| 37209825 | 2023 | The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation. | 2 |
| 34705524 | 2022 | Analysis of senescence-responsive stress fiber proteome reveals reorganization of stress fibers mediated by elongation factor eEF2 in HFF-1 cells. | 4 |
| 34705524 | 2022 | Analysis of senescence-responsive stress fiber proteome reveals reorganization of stress fibers mediated by elongation factor eEF2 in HFF-1 cells. | 4 |
| 33355653 | 2021 | De Novo variants in EEF2 cause a neurodevelopmental disorder with benign external hydrocephalus. | 9 |
| 33662272 | 2021 | PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation. | 8 |
| 33355653 | 2021 | De Novo variants in EEF2 cause a neurodevelopmental disorder with benign external hydrocephalus. | 9 |
| 33662272 | 2021 | PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation. | 8 |
| 32054489 | 2020 | The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2. | 15 |
| 32881411 | 2020 | miR-642a-5p partially mediates the effects of lipopolysaccharide on human pulmonary microvascular endothelial cells via eEF2. | 3 |
| 33057331 | 2020 | Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen. | 2 |
Citation
Dessen P
EEF2 (eukaryotic translation elongation factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40410/eef2-(eukaryotic-translation-elongation-factor-2)
