Identity
HGNC
LOCATION
5q21.3
LOCUSID
ALIAS
AF1,EFL5,EPLG7,GLC1M,LERK7,RAGS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1946
MIM: 601535
HGNC: 3225
Ensembl: ENSG00000184349
Variants:
dbSNP: 1946
ClinVar: 1946
TCGA: ENSG00000184349
COSMIC: EFNA5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000184349 | ENST00000333274 | P52803 |
| ENSG00000184349 | ENST00000509503 | D6RDV5 |
| ENSG00000184349 | ENST00000611503 | A0A087X240 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33389678 | 2021 | PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5. | 13 |
| 33893375 | 2021 | Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality. | 8 |
| 33389678 | 2021 | PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5. | 13 |
| 33893375 | 2021 | Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality. | 8 |
| 31988455 | 2020 | Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma. | 11 |
| 31988455 | 2020 | Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma. | 11 |
| 30352868 | 2019 | Mapping of breakpoints in balanced chromosomal translocations by shallow whole-genome sequencing points to EFNA5, BAHD1 and PPP2R5E as novel candidates for genes causing human Mendelian disorders. | 10 |
| 30352868 | 2019 | Mapping of breakpoints in balanced chromosomal translocations by shallow whole-genome sequencing points to EFNA5, BAHD1 and PPP2R5E as novel candidates for genes causing human Mendelian disorders. | 10 |
| 25663355 | 2016 | OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. | 32 |
| 27354374 | 2016 | Exosomes mediate cell contact-independent ephrin-Eph signaling during axon guidance. | 58 |
| 25663355 | 2016 | OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. | 32 |
| 27354374 | 2016 | Exosomes mediate cell contact-independent ephrin-Eph signaling during axon guidance. | 58 |
| 25993310 | 2015 | Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5. | 7 |
| 25993310 | 2015 | Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5. | 7 |
| 25300504 | 2014 | Mutational screening of EFNA5 in Chinese age-related cataract patients. | 12 |
Citation
Dessen P
EFNA5 (ephrin A5)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40414/efna5
