EGR3 (early growth response 3)

2003-11-01  

Identity

HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
EGR-3,PILOT
FUSION GENES

Other Information

Locus ID:

NCBI: 1960
MIM: 602419
HGNC: 3240
Ensembl: ENSG00000179388

Variants:

dbSNP: 1960
ClinVar: 1960
TCGA: ENSG00000179388
COSMIC: EGR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179388ENST00000317216Q06889
ENSG00000179388ENST00000519492E5RIM5
ENSG00000179388ENST00000522910Q06889

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Viral carcinogenesisKEGGhsa05203
Viral carcinogenesisKEGGko05203
Hepatitis BKEGGhsa05161

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384783842024Expression of Early Growth Response 3 in Skin Cancers.0
386571222024EGR3 Polymorphism Is a Potential Susceptibility Factor of Schizophrenia Risk in a Chinese Population.0
384783842024Expression of Early Growth Response 3 in Skin Cancers.0
386571222024EGR3 Polymorphism Is a Potential Susceptibility Factor of Schizophrenia Risk in a Chinese Population.0
363425112023Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells.1
371008822023The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.0
379997512023EGR3 and estrone are involved in the tamoxifen resistance and progression of breast cancer.0
363425112023Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells.1
371008822023The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.0
379997512023EGR3 and estrone are involved in the tamoxifen resistance and progression of breast cancer.0
331131632021Schizophrenia risk candidate EGR3 is a novel transcriptional regulator of RELN and regulates neurite outgrowth via the Reelin signal pathway in vitro.5
334853492021HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia.3
342437292021XIST promotes apoptosis and the inflammatory response in CSE-stimulated cells via the miR-200c-3p/EGR3 axis.18
331131632021Schizophrenia risk candidate EGR3 is a novel transcriptional regulator of RELN and regulates neurite outgrowth via the Reelin signal pathway in vitro.5
334853492021HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia.3

Citation

Dessen P

EGR3 (early growth response 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40420/egr3