ELF3 (E74 like ETS transcription factor 3)

2003-02-01  

Identity

HGNC
ELF3
LOCATION
1q32.1
LOCUSID
1999
ALIAS
EPR-1,ERT,ESE-1,ESX
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1999
MIM: 602191
HGNC: 3318
Ensembl: ENSG00000163435

Variants:

dbSNP: 1999
ClinVar: 1999
TCGA: ENSG00000163435
COSMIC: ELF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163435ENST00000359651P78545
ENSG00000163435ENST00000359651A0A024R974
ENSG00000163435ENST00000367283P78545
ENSG00000163435ENST00000367283A0A024R974
ENSG00000163435ENST00000367284P78545
ENSG00000163435ENST00000367284A0A024R974
ENSG00000163435ENST00000446188Q5SR36

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378328052024Expression of CD44 is regulated by ELF3 in 5-FU treated colorectal cancer cells.0
384818032024WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.0
390528362024HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.0
378328052024Expression of CD44 is regulated by ELF3 in 5-FU treated colorectal cancer cells.0
384818032024WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8.0
390528362024HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.0
363296202023ESE1/AGR2 axis antagonizes TGF-β-induced epithelial-mesenchymal transition in low-grade pancreatic cancer.4
365954972023MYB and ELF3 differentially modulate labor-inducing gene expression in myometrial cells.1
368404132023An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.7
369888912023ELF3 promotes gemcitabine resistance through PKMYT1/CDK1 signaling pathway in gallbladder cancer.2
363296202023ESE1/AGR2 axis antagonizes TGF-β-induced epithelial-mesenchymal transition in low-grade pancreatic cancer.4
365954972023MYB and ELF3 differentially modulate labor-inducing gene expression in myometrial cells.1
368404132023An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.7
369888912023ELF3 promotes gemcitabine resistance through PKMYT1/CDK1 signaling pathway in gallbladder cancer.2
345625992022WNT7B represses epithelial-mesenchymal transition and stem-like properties in bladder urothelial carcinoma.9

Citation

Dessen P

ELF3 (E74 like ETS transcription factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40439/gene-fusions/js/meetings/