Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22936
MIM: 601874
HGNC: 17064
Ensembl: ENSG00000118985
Variants:
dbSNP: 22936
ClinVar: 22936
TCGA: ENSG00000118985
COSMIC: ELL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000118985 | ENST00000237853 | O00472 |
| ENSG00000118985 | ENST00000508757 | H0Y8G1 |
| ENSG00000118985 | ENST00000513343 | D6RC27 |
| ENSG00000118985 | ENST00000635633 | A0A0U1RR08 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| RNA polymerase II transcribes snRNA genes | REACTOME | R-HSA-6807505 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34265249 | 2021 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. | 9 |
| 34948391 | 2021 | Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation. | 0 |
| 34265249 | 2021 | Allosteric transcription stimulation by RNA polymerase II super elongation complex. | 9 |
| 34948391 | 2021 | Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation. | 0 |
| 29179998 | 2018 | ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells. | 7 |
| 29695719 | 2018 | The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression. | 17 |
| 30009504 | 2018 | Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells. | 6 |
| 30556882 | 2018 | Upregulation of long noncoding RNA MRCCAT1 predicts poor prognosis and functions as an oncogene in glioma. | 2 |
| 29179998 | 2018 | ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells. | 7 |
| 29695719 | 2018 | The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression. | 17 |
| 30009504 | 2018 | Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells. | 6 |
| 30556882 | 2018 | Upregulation of long noncoding RNA MRCCAT1 predicts poor prognosis and functions as an oncogene in glioma. | 2 |
| 28134250 | 2017 | Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription. | 17 |
| 28531325 | 2017 | Up-regulated microRNA-299 corrected with poor prognosis of glioblastoma multiforme patients by targeting ELL2. | 9 |
| 28858629 | 2017 | Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival. | 8 |
Citation
Dessen P
ELL2 (elongation factor for RNA polymerase II 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40445/ell2
