EN1 (engrailed homeobox 1)

2003-05-01  

Identity

HGNC
LOCATION
2q14.2
LOCUSID
ALIAS
ENDOVESLB

Other Information

Locus ID:

NCBI: 2019
MIM: 131290
HGNC: 3342
Ensembl: ENSG00000163064

Variants:

dbSNP: 2019
ClinVar: 2019
TCGA: ENSG00000163064
COSMIC: EN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163064ENST00000295206Q05925

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381535092024The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding.0
382821212024TGFβ-induced EN1 promotes tumor budding of adenoid cystic carcinoma in patient-derived organoid model.0
384181832024[En1 promotes cell proliferation and migration via Hedgehog signaling pathway in esophageal squamous cell carcinoma].0
381535092024The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding.0
382821212024TGFβ-induced EN1 promotes tumor budding of adenoid cystic carcinoma in patient-derived organoid model.0
384181832024[En1 promotes cell proliferation and migration via Hedgehog signaling pathway in esophageal squamous cell carcinoma].0
351630432022EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling.10
351630432022EN1 Regulates Cell Growth and Proliferation in Human Glioma Cells via Hedgehog Signaling.10
333336162021Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma.4
338500162021Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution.19
342598302021Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.8
344710942021Converting fibroblastic fates leads to wound healing without scar.5
333336162021Homeobox transcription factor engrailed homeobox 1 is a possible diagnostic marker for adenoid cystic carcinoma and polymorphous adenocarcinoma.4
338500162021Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution.19
342598302021Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.8

Citation

Dessen P

EN1 (engrailed homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40450/en1