Identity
HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
EPLIN,LDLCQ8,SREBP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51474
MIM: 608364
HGNC: 24636
Ensembl: ENSG00000050405
Variants:
dbSNP: 51474
ClinVar: 51474
TCGA: ENSG00000050405
COSMIC: LIMA1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38185251 | 2024 | Nuclear-cytoplasmic translocation of SQSTM1/p62 protein enhances ESCC cell migration and invasion by stabilizing EPLIN expression. | 1 |
| 38719752 | 2024 | The concerted action of SEPT9 and EPLIN modulates the adhesion and migration of human fibroblasts. | 0 |
| 38185251 | 2024 | Nuclear-cytoplasmic translocation of SQSTM1/p62 protein enhances ESCC cell migration and invasion by stabilizing EPLIN expression. | 1 |
| 38719752 | 2024 | The concerted action of SEPT9 and EPLIN modulates the adhesion and migration of human fibroblasts. | 0 |
| 37325974 | 2023 | EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration. | 1 |
| 37752233 | 2023 | MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex. | 3 |
| 37325974 | 2023 | EPLIN-β is a novel substrate of ornithine decarboxylase antizyme 1 and mediates cellular migration. | 1 |
| 37752233 | 2023 | MAD2 activates IGF1R/PI3K/AKT pathway and promotes cholangiocarcinoma progression by interfering USP44/LIMA1 complex. | 3 |
| 36497115 | 2022 | CAF-Released Exosomal miR-20a-5p Facilitates HCC Progression via the LIMA1-Mediated β-Catenin Pathway. | 13 |
| 36497115 | 2022 | CAF-Released Exosomal miR-20a-5p Facilitates HCC Progression via the LIMA1-Mediated β-Catenin Pathway. | 13 |
| 33999101 | 2021 | Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. | 11 |
| 34356662 | 2021 | Epithelial Protein Lost in Neoplasm, EPLIN, the Cellular and Molecular Prospects in Cancers. | 10 |
| 33999101 | 2021 | Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. | 11 |
| 34356662 | 2021 | Epithelial Protein Lost in Neoplasm, EPLIN, the Cellular and Molecular Prospects in Cancers. | 10 |
| 32496561 | 2020 | LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. | 14 |
Citation
Dessen P
LIMA1 (LIM domain and actin binding 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40474/lima1
