Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2069
MIM: 602061
HGNC: 3443
Ensembl: ENSG00000124882
Variants:
dbSNP: 2069
ClinVar: 2069
TCGA: ENSG00000124882
COSMIC: EREG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124882 | ENST00000244869 | O14944 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10040 | cetuximab | Chemical | Pathway | associated | |||
| PA162373091 | panitumumab | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38250159 | 2024 | IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer. | 1 |
| 38514807 | 2024 | The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex. | 1 |
| 38945975 | 2024 | Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma. | 0 |
| 38250159 | 2024 | IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer. | 1 |
| 38514807 | 2024 | The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex. | 1 |
| 38945975 | 2024 | Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma. | 0 |
| 36730878 | 2023 | Two Cases of Biphasic Synovial Sarcoma With Expression of PAX8 and ER: A Diagnostic Pitfall. | 0 |
| 37329522 | 2023 | MicroRNA-1179 targets Epiregulin (EREG) regulates the proliferation and metastasis of human multiple myeloma cells. | 1 |
| 36730878 | 2023 | Two Cases of Biphasic Synovial Sarcoma With Expression of PAX8 and ER: A Diagnostic Pitfall. | 0 |
| 37329522 | 2023 | MicroRNA-1179 targets Epiregulin (EREG) regulates the proliferation and metastasis of human multiple myeloma cells. | 1 |
| 35491469 | 2022 | Differentially expressed EREG and SPP1 are independent prognostic markers in cervical squamous cell carcinoma. | 4 |
| 35551652 | 2022 | Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling. | 7 |
| 35491469 | 2022 | Differentially expressed EREG and SPP1 are independent prognostic markers in cervical squamous cell carcinoma. | 4 |
| 35551652 | 2022 | Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling. | 7 |
| 33640382 | 2021 | Role of the calcium-sensing receptor (CaSR) in cancer metastasis to bone: Identifying a potential therapeutic target. | 11 |
Citation
Dessen P
EREG (epiregulin)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40484/ereg
