DCBLD2 (discoidin, CUB and LCCL domain containing 2)

2003-02-01  

Identity

HGNC
LOCATION
3q12.1
LOCUSID
ALIAS
CLCP1,ESDN
FUSION GENES

Other Information

Locus ID:

NCBI: 131566
MIM: 608698
HGNC: 24627
Ensembl: ENSG00000057019

Variants:

dbSNP: 131566
ClinVar: 131566
TCGA: ENSG00000057019
COSMIC: DCBLD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000057019ENST00000326840Q96PD2
ENSG00000057019ENST00000326857Q96PD2
ENSG00000057019ENST00000449482C9JIW6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377810452023cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence.2
378564232023CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.1
377810452023cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence.2
378564232023CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway.1
362529122022miR-451a suppresses papillary thyroid cancer cell proliferation and invasion and facilitates apoptosis through targeting DCBLD2 and AKT1.3
362529122022miR-451a suppresses papillary thyroid cancer cell proliferation and invasion and facilitates apoptosis through targeting DCBLD2 and AKT1.3
337888132021Transmembrane protein DCBLD2 is correlated with poor prognosis and affects phenotype by regulating epithelial-mesenchymal transition in human glioblastoma cells.3
338621512021ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3.2
341453212021A homozygous nonsense mutation in DCBLD2 is a candidate cause of developmental delay, dysmorphic features and restrictive cardiomyopathy.5
337888132021Transmembrane protein DCBLD2 is correlated with poor prognosis and affects phenotype by regulating epithelial-mesenchymal transition in human glioblastoma cells.3
338621512021ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3.2
341453212021A homozygous nonsense mutation in DCBLD2 is a candidate cause of developmental delay, dysmorphic features and restrictive cardiomyopathy.5
321665822020Association of DCBLD2 upregulation with tumor progression and poor survival in colorectal cancer.13
326060172020FYN and ABL Regulate the Interaction Networks of the DCBLD Receptor Family.4
321665822020Association of DCBLD2 upregulation with tumor progression and poor survival in colorectal cancer.13

Citation

Dessen P

DCBLD2 (discoidin, CUB and LCCL domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40498/cancer-prone-explorer/cancer-prone-explorer/js/_common.js