Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2135
MIM: 602411
HGNC: 3516
Ensembl: ENSG00000162694
Variants:
dbSNP: 2135
ClinVar: 2135
TCGA: ENSG00000162694
COSMIC: EXTL2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36181793 | 2022 | Glycosyltransferases EXTL2 and EXTL3 cellular balance dictates heparan sulfate biosynthesis and shapes gastric cancer cell motility and invasion. | 3 |
| 36181793 | 2022 | Glycosyltransferases EXTL2 and EXTL3 cellular balance dictates heparan sulfate biosynthesis and shapes gastric cancer cell motility and invasion. | 3 |
| 32517548 | 2021 | Altered Expression of Aggrecan, FAM20B, B3GALT6, and EXTL2 in Patients with Osteoarthritis and Kashin-Beck Disease. | 4 |
| 32517548 | 2021 | Altered Expression of Aggrecan, FAM20B, B3GALT6, and EXTL2 in Patients with Osteoarthritis and Kashin-Beck Disease. | 4 |
| 32703234 | 2020 | The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. | 12 |
| 32703234 | 2020 | The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. | 12 |
| 23395820 | 2013 | EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner. | 48 |
| 23395820 | 2013 | EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner. | 48 |
| 19690583 | 2010 | Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses. | 21 |
| 19690583 | 2010 | Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses. | 21 |
| 15831490 | 2005 | Two-step mechanism that determines the donor binding specificity of human UDP-N-acetylhexosaminyltransferase. | 4 |
| 15831490 | 2005 | Two-step mechanism that determines the donor binding specificity of human UDP-N-acetylhexosaminyltransferase. | 4 |
Citation
Dessen P
EXTL2 (exostosin like glycosyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40515/extl2
