Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2152
MIM: 134390
HGNC: 3541
Ensembl: ENSG00000117525
Variants:
dbSNP: 2152
ClinVar: 2152
TCGA: ENSG00000117525
COSMIC: F3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117525 | ENST00000334047 | P13726 |
| ENSG00000117525 | ENST00000370207 | P13726 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446459 | Myocardial Ischemia | Disease | ClinicalAnnotation | associated | PD | 19027114 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 19027114 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37201535 | 2024 | Human Genetic Variation in F3 and Its Impact on Tissue Factor-Dependent Disease. | 0 |
| 38191673 | 2024 | Tissue factor overexpression promotes resistance to KRAS-G12C inhibition in non-small cell lung cancer. | 1 |
| 37201535 | 2024 | Human Genetic Variation in F3 and Its Impact on Tissue Factor-Dependent Disease. | 0 |
| 38191673 | 2024 | Tissue factor overexpression promotes resistance to KRAS-G12C inhibition in non-small cell lung cancer. | 1 |
| 36696180 | 2023 | Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease. | 10 |
| 36980251 | 2023 | The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor. | 1 |
| 37263122 | 2023 | Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis. | 5 |
| 37377751 | 2023 | CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation. | 3 |
| 37511344 | 2023 | High CD142 Level Marks Tumor-Promoting Fibroblasts with Targeting Potential in Colorectal Cancer. | 1 |
| 37583699 | 2023 | Tissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis. | 1 |
| 37589138 | 2023 | Cell Surface Platelet Tissue Factor Expression: Regulation by P2Y(12) and Link to Residual Platelet Reactivity. | 0 |
| 38069209 | 2023 | Expression of Tissue Factor and Platelet/Leukocyte Markers on Extracellular Vesicles Reflect Platelet-Leukocyte Interaction in Severe COVID-19. | 1 |
| 36696180 | 2023 | Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease. | 10 |
| 36980251 | 2023 | The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor. | 1 |
| 37263122 | 2023 | Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis. | 5 |
Citation
Dessen P
F3 (coagulation factor III, tissue factor)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40522/f3
