Identity
HGNC
LOCATION
4q28.1
LOCUSID
ALIAS
CDHF14,CDHR11,FAT-J,FATJ,HKLLS2,NBLA00548,VMLDS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79633
MIM: 612411
HGNC: 23109
Ensembl: ENSG00000196159
Variants:
dbSNP: 79633
ClinVar: 79633
TCGA: ENSG00000196159
COSMIC: FAT4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196159 | ENST00000335110 | Q6V0I7 |
| ENSG00000196159 | ENST00000394329 | Q6V0I7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hippo signaling pathway -multiple species | KEGG | ko04392 |
| Hippo signaling pathway -multiple species | KEGG | hsa04392 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35770846 | 2023 | Increased expression of FAT4 suppress metastasis of lung adenocarcinoma through regulating MAPK pathway and associated with immune cells infiltration. | 1 |
| 36797229 | 2023 | Structure of the planar cell polarity cadherins Fat4 and Dachsous1. | 1 |
| 36811800 | 2023 | Identification of FAT4 as a positive prognostic biomarker in DLBCL by comprehensive genomic analysis. | 0 |
| 37751246 | 2023 | Prognostic Impact of FSTL3, ADAM12, and FAT4 in Patients of Colon Cancer: Clinicopathologic Study. | 0 |
| 38055646 | 2023 | FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathways. | 0 |
| 35770846 | 2023 | Increased expression of FAT4 suppress metastasis of lung adenocarcinoma through regulating MAPK pathway and associated with immune cells infiltration. | 1 |
| 36797229 | 2023 | Structure of the planar cell polarity cadherins Fat4 and Dachsous1. | 1 |
| 36811800 | 2023 | Identification of FAT4 as a positive prognostic biomarker in DLBCL by comprehensive genomic analysis. | 0 |
| 37751246 | 2023 | Prognostic Impact of FSTL3, ADAM12, and FAT4 in Patients of Colon Cancer: Clinicopathologic Study. | 0 |
| 38055646 | 2023 | FAT4 loss initiates hepatocarcinogenesis through the switching of canonical to noncanonical WNT signaling pathways. | 0 |
| 36051999 | 2022 | A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors. | 2 |
| 36051999 | 2022 | A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors. | 2 |
| 34130359 | 2021 | FAT4 identified as a potential modifier of orofacial cleft laterality. | 3 |
| 34130359 | 2021 | FAT4 identified as a potential modifier of orofacial cleft laterality. | 3 |
| 32366234 | 2020 | FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer. | 9 |
Citation
Dessen P
FAT4 (FAT atypical cadherin 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-10-01
Online version: http://atlasgeneticsoncology.org/gene/40537/fat4
