FGF11 (fibroblast growth factor 11)

2003-02-01  

Identity

HGNC
FGF11
LOCATION
17p13.1
LOCUSID
2256
ALIAS
FGF-11,FHF-3,FHF3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2256
MIM: 601514
HGNC: 3667
Ensembl: ENSG00000161958

Variants:

dbSNP: 2256
ClinVar: 2256
TCGA: ENSG00000161958
COSMIC: FGF11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161958ENST00000293829Q92914
ENSG00000161958ENST00000572907I3L4N4
ENSG00000161958ENST00000575082I3L4N4
ENSG00000161958ENST00000575235I3L4N4
ENSG00000161958ENST00000575398I3L4N4

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Regulation of actin cytoskeletonKEGGko04810
MelanomaKEGGko05218
MAPK signaling pathwayKEGGhsa04010
Regulation of actin cytoskeletonKEGGhsa04810
Pathways in cancerKEGGhsa05200
MelanomaKEGGhsa05218
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Phase 0 - rapid depolarisationREACTOMER-HSA-5576892
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376469222023Fibroblast Growth Factor 11 Inhibits Hepatitis B Virus Gene Expression Through FXRα Suppression.0
376469222023Fibroblast Growth Factor 11 Inhibits Hepatitis B Virus Gene Expression Through FXRα Suppression.0
354302722022Hypoxia promotes thyroid cancer progression through HIF1α/FGF11 feedback loop.6
363183592022Expression and purification of intracrine human FGF 11 and study of its FGFR-dependent biological activity.2
354302722022Hypoxia promotes thyroid cancer progression through HIF1α/FGF11 feedback loop.6
363183592022Expression and purification of intracrine human FGF 11 and study of its FGFR-dependent biological activity.2
333498422021Targeted sequencing of Parkinson's disease loci genes highlights SYT11, FGF20 and other associations.23
344044352021Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway.11
333498422021Targeted sequencing of Parkinson's disease loci genes highlights SYT11, FGF20 and other associations.23
344044352021Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway.11
309845502019FGF11 influences 3T3-L1 preadipocyte differentiation by modulating the expression of PPARγ regulators.8
309845502019FGF11 influences 3T3-L1 preadipocyte differentiation by modulating the expression of PPARγ regulators.8
298521652018T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling.19
298521652018T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling.19
280273902017FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.16

Citation

Dessen P

FGF11 (fibroblast growth factor 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40551/case-report-explorer/teaching-explorer/favicon/js/lib/zoomerang.js