Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55106
MIM: 614955
HGNC: 25500
Ensembl: ENSG00000172123
Variants:
dbSNP: 55106
ClinVar: 55106
TCGA: ENSG00000172123
COSMIC: SLFN12
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37165099 | 2023 | Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells. | 7 |
| 37165099 | 2023 | Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells. | 7 |
| 34272366 | 2021 | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. | 24 |
| 34272366 | 2021 | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. | 24 |
| 30875077 | 2019 | Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells. | 10 |
| 31026779 | 2019 | Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation. | 10 |
| 31420216 | 2019 | Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover. | 30 |
| 31838790 | 2019 | Schlafen12 Reduces the Aggressiveness of Triple Negative Breast Cancer through Post-Transcriptional Regulation of ZEB1 That Drives Stem Cell Differentiation. | 12 |
| 30875077 | 2019 | Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells. | 10 |
| 31026779 | 2019 | Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation. | 10 |
| 31420216 | 2019 | Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover. | 30 |
| 31838790 | 2019 | Schlafen12 Reduces the Aggressiveness of Triple Negative Breast Cancer through Post-Transcriptional Regulation of ZEB1 That Drives Stem Cell Differentiation. | 12 |
| 30045019 | 2018 | Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. | 24 |
| 30045019 | 2018 | Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. | 24 |
| 29107068 | 2017 | Targeting tumor cells based on Phosphodiesterase 3A expression. | 16 |
Citation
Dessen P
SLFN12 (schlafen family member 12)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40581/slfn12
