Identity
HGNC
LOCATION
5p15.31
LOCUSID
ALIAS
MISU,MRT5,SAKI,TRM4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54888
MIM: 610916
HGNC: 25994
Ensembl: ENSG00000037474
Variants:
dbSNP: 54888
ClinVar: 54888
TCGA: ENSG00000037474
COSMIC: NSUN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000037474 | ENST00000264670 | Q08J23 |
| ENSG00000037474 | ENST00000504374 | A0A140T9Y7 |
| ENSG00000037474 | ENST00000506139 | Q08J23 |
| ENSG00000037474 | ENST00000514127 | A0A140T9Z1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38237738 | 2024 | NSUN2-Mediated m(5)C Methylation Impairs Endometrial Receptivity. | 0 |
| 38387687 | 2024 | LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1. | 0 |
| 38403250 | 2024 | 5-Methylcytosine transferase NSUN2 drives NRF2-mediated ferroptosis resistance in non-small cell lung cancer. | 0 |
| 38411298 | 2024 | NSUN2 promotes lung adenocarcinoma progression through stabilizing PIK3R2 mRNA in an m(5)C-dependent manner. | 0 |
| 38764010 | 2024 | NSUN2 affects diabetic retinopathy progression by regulating MUC1 expression through RNA m(5)C methylation. | 0 |
| 38844963 | 2024 | NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m(5)C methylation. | 0 |
| 38237738 | 2024 | NSUN2-Mediated m(5)C Methylation Impairs Endometrial Receptivity. | 0 |
| 38387687 | 2024 | LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1. | 0 |
| 38403250 | 2024 | 5-Methylcytosine transferase NSUN2 drives NRF2-mediated ferroptosis resistance in non-small cell lung cancer. | 0 |
| 38411298 | 2024 | NSUN2 promotes lung adenocarcinoma progression through stabilizing PIK3R2 mRNA in an m(5)C-dependent manner. | 0 |
| 38764010 | 2024 | NSUN2 affects diabetic retinopathy progression by regulating MUC1 expression through RNA m(5)C methylation. | 0 |
| 38844963 | 2024 | NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m(5)C methylation. | 0 |
| 36183976 | 2023 | NSUN2-mediated mRNA m(5)C Modification Regulates the Progression of Hepatocellular Carcinoma. | 9 |
| 36529349 | 2023 | NSUN2 gene rs13181449 C>T polymorphism reduces neuroblastoma risk. | 8 |
| 36792587 | 2023 | NSUN2 promotes osteosarcoma progression by enhancing the stability of FABP5 mRNA via m(5)C methylation. | 10 |
Citation
Dessen P
NSUN2 (NOP2/Sun RNA methyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40599/nsun2
